Chinese Academy of Sciences

Stmicroelectronics International N.v.

Shanghai Jiaotong University

Stmicroelectronics (shenzhen) R&d Co. Ltd.

Stmicroelectronics (china) Investment Co. Ltd

Yan Zhang

Dino Costanzo

Jian Ding

Meiyu Geng

Ao Zhang

Huan Shi

Huihui Zhang

Chengpan Cai

Yanjie Sun

Fubin Li

Yingjie Zhao

Xiaobo Liu

Guixi Sun

Chunyong Ding

Ancheng Shen

Zuoquan Xie

Xiyuan Wang

Various examples in accordance with the present disclosure provide systems, apparatuses, methods, and computer program products associated with detecting phase fault in a motor, such as unbalance phase and phase loss fault.

Systems, apparatuses, methods, and computer program products for detecting unbalance phase and phase loss fault for motor control

A fluorine-containing substituted benzothiophene compound and a pharmaceutical composition and an application thereof are described. The compound has the structure as shown in formula (I), in which the definitions of each group and substituent are as described in the description. A preparation method of the compound and an anti-tumor application thereof are also described.

Fluorine-containing substituted benzothiophene compound, and pharmaceutical composition and application thereof

A three-phase load is powered by an SPWM driven inverter having a single shunt-topology. During operation, drain-to-source resistances of transistors of each branch of the inverter are determined. Interpolation is performed on assumed drain-to-source resistances of the transistors for different temperatures to produce a non-linear model of drain-to-source resistance to temperature for the transistors, and the drain-to-source resistances determined during operation and the non-linear model are used to estimate temperature values of the transistors. Driving of the inverter can be adjusted so that conductivity of each branch is set so that power delivered by that branch is as high as possible without exceeding an allowed drain current threshold representing a threshold junction temperature. In addition, driving of the inverter can be ceased if the temperature of a transistor exceeds the threshold temperature.

Inverter and method to measure junction temperature for thermal protection

Provided herein is a heavy chain constant region comprising a CH1 domain, a hinge region, a CH2 domain and a CH3 domain, wherein the sequences of said CH1 domain and hinge region derive from the sequences of CH1 domain and hinge region in human IgG2, the sequences of said CH2 domain and CH3 domain derive from the sequences of CH2 domain and CH3 domain in human IgGs; and wherein, said antibody heavy chain constant region has an affinity to human FcγRIIB equal to or higher than the affinity of human IgG1 to human FcγRIIB, said antibody heavy chain constant region has an I/A ratio equal to or higher than human IgG1 has. Also provided are antibodies or fusion proteins based on a heavy chain constant region according to the above, wherein the antibody heavy chain constant region significantly enhances agonistic activity of the antibodies or fusion proteins and improves efficacy of the antibodies or fusion proteins in treating diseases like tumors and autoimmune diseases.

Sequence of antibody heavy chain constant region for enhancing agonistic antibody activity

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Shanghai, China

Yan Zhang