Tasly Pharmaceutical Group Co., Ltd.

Jenkem Technologyco., Ltd.. (tianjin)

China National Offshore Oil Corporation

Cnooc Tianjin Chemical Research & Design Institute Co. Ltd.

Cnooc Energy Technology & Services Limited

Institute of Pharmacology and Toxicology Academy of Military Medical Sciences Pla China

Jenkem Technology Co., Ltd.

Yan Liu

Xuan Zhao

Xijun Yan

Zewang Feng

Naifeng Wu

Zhengliang Ye

Hui Zhu

Jinliang Wang

Peng Liu

Zhenguo Wang

Zhixin Guo

Meina Lin

Shunnan Zhang

Xiaolin Bai

Bin Li

Jian Li

Lijun Fan

Yan Sun

Yongfeng Zheng

Lina Dong

Jianhui Yang

Song Gao

Bo Xu

Xingyun Shao

Yueqiu Pan

Xunzhi Zhao

Zhiyu Sui

Chang Shu

Jingxin Fan

Jiazhong Zang

Haibin Yu

Hong Cheng

Bernard Meunier

Michel Nguyen

Dean Wang

Shupeng Li

Xiaowei Song

Fan Chen

Pengcheng Yin

Lili Guo

Qiang Niu

Ju Huang

Anne Robert

Weixin Zhang

Xingguo Liu

Yue Zhang

Yingge Zhang

Hongjuan Yao

Lan Sun

The present disclosure relates to a method for a simulated moving bed to adsorb and separate polycyclic aromatic hydrocarbons. Zeolite, metal oxide and metal-modified materials are employed as adsorbent. Firstly, diesel oil flows through pre-treatment adsorbent to remove the trace amount of impurities. Secondly, the purified diesel oil flows through the simulated moving bed so that the PAHs can be separated from diesel oil. In this process, the valves are switched periodically, leading to the relative movement of adsorption beds. At the same time, desorbent is pumped into the equipment to wash out PAHs, achieving the continuous adsorption-regeneration operation. Thirdly, simple distillation is employed to separate desorbent from clean diesel oil and PAHs, respectively. Finally, the fractions of clean diesel oil and PAHs can be obtained, respectively. The separated desorbent can be recycled. The PAHs removal rate can reach to 90%.

Method for simulated moving bed to adsorb and separate polycyclic aromatic hydrocarbons

A conjugate represented by general formula (I), wherein Ris a Calkyl, B is an anesthetic, and A is a linking group, and a quaternary ammonium salt is formed at the linking position between B and R. The conjugate has a prolonged analgesic effect, and can be used in postoperative analgesia or treatment for chronic pain.

Conjugate of polyethylene glycol and anesthetic, and preparation method thereof

Disclosed are a compound of Formula I, having higher inhibition of protein kinase G (PKG) activity and pharmaceutically acceptable salts thereof. In Formula I, Rand Rare the same or different, each being independently chosen from the halogens, the C-Calkoxyl group, the C-Calkyl group, the C-Calkenyl group, and the C-Calkynyl group; Ris chosen from H, the halogens, the substituted or unsubstituted C-Calkyl group, C-Ccycloalkyl group, C-Calkenyl group, and C-Calkynyl group, aryl group, and heteroaryl group; and n is an integer between 0 and 15. Also disclosed is a pharmaceutical composition comprising said compound, the use of the compound in treating pains, in particular chronic pain, a preparation method for the compound, and a new intermediate.

Compound having higher inhibitory activity on protein kinase G and preparation method thereof

A pharmaceutical composition for treating headache, prepared from eleven Chinese herbal medicines: Chinese angelica root,, prepared rhizome of rehmannia, uncaria tomentosa, leatherleaf milletia, prunella vulgaris, sicklesenna seed, pearl shell,tuber, and, and a proper amount of adjuvant materials. A preparation method of the pharmaceutical composition, and uses thereof in the preparation of drugs for treating various headaches, traumatic cranial nerve syndrome, dizziness and vertigo, vexation and irritability, insomnia and dreaminess.

Pharmaceutical composition for treating headache, and preparation method thereof

This invention provides a composition for heart disease comprising extracts from raw herbs of 80.0-97.0% Radix, 1.0-19.0%and 0.1-1.0% Borneol and its active ingredients. This invention also provides a method for preparing said composition and the active ingredients of the composition. Finally, this invention provides various uses of said compositions and the active ingredients.

Composition for heart disease, its active ingredients, method to prepare same and uses thereof

This invention provides compositions comprising extracts of Radix Salviae Miltiorrhizae, Radix Notoginseng and Borneol. Said compositions comprise notoginsenoside Rand ginsenoside Rwhich are active components for therapeutic applications. This invention also provides a method of preparation of the said compositions and a method of identification and determination of the amount of individual effective components of said compositions. Finally, this invention provides various uses of the compositions.

Herbal composition for angina pectoris, method to prepare same and uses thereof

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Tianjin, China

Yan Liu