Universitatsklinikum Hamburg-Eppendorf

Universitaetsklinikum Hamburg-Eppendorf

Tissue Systems Holding Gmbh

Yalin Yildirim

Thomas Eschenhagen

Wolfram-Hubertus Zimmermann

Hermann Reichenspurner

Simon Pecha

The invention is directed to a pouch-like construct comprising mammalian tissue which can be used for preventing distension and/or resisting dilation of the heart in a mammal. Preferably, the pouch-like tissue construct has contractile properties. The invention further relates to a method for the preparation of a pouch-like construct comprising mammalian tissue which can be used for the above purposes.

Pouch-like construct for preventing heart distension

An implantable valve prosthesis for preventing blood reflux from a cardiac atrium into a vein opening into the atrium, with a generally tubular stent (), also a flexible tube () that can be closed by collapsing the tube () and which is arranged at least in a partial area of a second end section () of the stent () on the outer peripheral surface. The second end opening () of the flexible tube () is open in the pressureless state. As a result of this valve design, during a physiological flow out of the pulmonary vein in the direction of the left atrium or out of the caval vein in the direction of the right atrium, there is no rise or an only insubstantial rise in the resistance to flow.

Implantable valve prosthesis

Growing community of inventors

Hamburg, Germany

Yalin Yildirim