Incyte Genomics, Inc.

Incyte Corporation

Incyte Pharmaceuticals, Inc.

Yalda Azimzai

Henry Yue

Mariah R Baughn

Jennifer L Hillman

Neil C Corley

Preeti G Lal

Karl J Guegler

Y Tom Tang

Olga Bandman

Matthew R Kaser

Gina A Gorgone

Dyung Aina M Lu

Janice K Au-Young

Jeffrey J Seilhamer

Michael Graham Walker

April J A Hafalia

Monique G Yao

Ameena R Gandhi

Yan Lu

Chandra S Arvizu

Tod M Klingler

Craig H Ison

Neil Burford

Danniel B Nguyen

Wayne D Volkmuth

Bridget A Warren

Junming Yang

Vicki S Elliott

Li Ding

Scott R Panzer

Narinder K Chawla

Rajagopal Gururajan

Gary B Zweiger

Catherine M Tribouley

Michael B Thornton

Jayalaxmi Ramkumar

Mary Jane Cunningham

Kavitha Thangavelu

Gregory Marcus

Jennifer L Policky

Liam Kearney

John D Burrill

Dyung Aina Lu

Amy K W Lasek

Y Tom Yang

Kurt A Zingler

Preeti G Lai

The invention provides human human kinases (PKIN) and polynucleotides which identify and encode PKIN. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of PKIN.

Human cAMP-dependent protein kinase beta-catalytic subunit

The invention provides a transmembrane protein that is differentially expressed in neoplastic disorders. It also provides for the use of the protein, a cDNA encoding the protein, and antibodies that specifically bind the protein in various methods to diagnose, stage, treat, or monitor the treatment of a neoplastic disorder.

Transmembrane protein differentially expressed in cancer

The invention provides human oxidoreductase molecules (OXRE) and polynucleotides which identify and encode OXRE. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of OXRE.

DNA encoding oxidoreductase and polypeptide encoded thereby

The invention provides human ubiquitin-conjugating enzyme homologs (UCEH) and polynucleotides which identify and encode UCEH. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of UCEH.

Human ubiquitin-conjugating enzyme homologs

The invention provides human transferase proteins (TRNSFS) and polynucleotides which identify and encode TRNSFS. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provide methods for diagnosing, treating, or preventing disorders, associated with expression of TRNSFS.

Human transferase proteins

The present invention relates to mammalian nucleic acid and protein molecules comprising a plurality of nucleic acid and protein molecules. The mammalian nucleic acid molecules can be used as hybridizable array elements in a microarray in diagnostic and therapeutic applications including detecting metabolic and toxicological responses, and in monitoring drug mechanism of action. The protein molecules can be used in a pharmaceutical composition. The present invention also relates to methods for screening compounds and therapeutics for metabolic responses indicative of a toxic compound or molecule.

Mammalian toxicological response markers

The invention provides novel kidney disease-associated genes and polypeptides encoded by those genes. The invention also provides expression vectors, host cells, and antibodies. The invention also provides methods for diagnosing, treating or preventing diseases of the kidney.

Genes associated with diseases of the kidney

The invention provides human ubiquitin-conjugating enzyme homologs (UCEH) and polynucleotides which identify and encode UCEH. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of

Nucleic acids encoding human ubiquitin-conjugating enzyme homologs

The invention provides human protein kinase homologs (PKH) and polynucleotides which identify and encode PKH. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of PKH.

Protein kinase homologs

The invention provides novel nucleic acid molecules and encoded proteins associated with response to polycyclic aromatic hydrocarbon exposure. The invention also provides expression vectors, host cells, and antibodies. The invention also provides methods for screening or purifying ligands and diagnosing, treating or preventing disorders associated with polycyclic aromatic hydrocarbon exposure.

Polycyclic aromatic hydrocarbon induced molecules

The invention provides novel developmentally-regulated hippocampal genes and polypeptides encoded by those genes. The invention also provides expression vectors, host cells, and antibodies. The invention also provides methods for diagnosing, treating or preventing diseases associated with hippocampus.

Molecules expressed in hippocampus

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Castro Valley, CA, United States of America

Yalda Azimzai