The Procter Gamble Company

Mars, Incorporated

The Gillette Company

Yakang Lin

John Christian Haught

Koti Tatachar Sreekrishna

Steven Hamilton Hoke

Michael Reilly

Ping Hu

Lori Ann Reinsalu

Qingxin Lei

Jean Soon Park

Ashraf Traboulsi

Kotikanyadanam Tatachar Sreekrishna

Pierig Jean-Marie Lepont

Carrita Anne Hightower

Timothy Woodrow Coffindaffer

Lowell Alan Sanker

Wenzhu Zhao

Christine Marie Cahen

Jason William Newlon

Safa Motlagh

Helen Rochelle Kemp

Katharine Anne Bakes

Koti Tatachar Sreekishna

Cathy Renee Schinaman

Molly Christine Findley

Koti Sreekrishna

The present invention relates to compositions containing plant materials or extracts with inhibitory effect on a 5-HTand/or NK-1 receptor for preventing or treating idiopathic vomiting.

Dietary composition for preventing, reducing, alleviating or treating idiopathic vomiting

Compositions containing one or more compounds with inhibitory effect on a 5-HT3a and/or NK-1 receptor are effective for preventing or treating idiopathic vomiting in a mammal.

Composition and method for preventing, reducing, alleviating or treating idiopathic vomiting

The present invention relates to compositions containing plant materials or extracts with inhibitory effect on a 5-HT3a and/or NK-1 receptor for preventing or treating idiopathic vomiting.

Dietary composition and method for preventing, reducing, alleviating or treating idiopathic vomiting

A method for screening compounds and compositions that reduce cetyl pyridinium chloride activation of TRPA1 receptor or TRPV1 receptor.

Reduction in CPC taste aversion by reducing CPC activation of TRPA1, TPRV1, or both

A means of isolating specific stereoisomers and enantiomers from a complex mixture containing a possibility of 32 different stereoconfigurations, thus concentrating the stereoisomer or enantiomer to a high degree of purity.

Method of chromatographic separation

Personal care compositions, such as oral medication compositions containing a flavor system comprising one or more coolants. The pleasant cool sensation provided by a coolant is enhanced in terms of quicker onset, greater intensity, impact or longer duration, which improves appeal and acceptability of the compositions to consumers.

Medications for deposition on biological surfaces

Oral care compositions having improved taste, said compositions comprising: a carrier material; from about 0.001 to about 10%, by weight of the composition, of an oral care component selected from metal salts, antimicrobial agents, bad breath reduction agents, bleaching agents, surfactants, or a combination thereof; and from about 0.0001 to about 1%, by weight of the composition, of a TRPA1 agonist selected from vanillin esters; benzoate esters; hydroxybenzoate derivatives; methoxy benzoate derivatives; hydroxybutanedioate derivatives; benzamidobenzoate derivatives; methylpropanoate derivatives; phenyl acetate derivatives; hex-3-enoate derivatives; 2-(furan-2-ylmethylsulfanyl)-3-methylpyrazine; phenylmethoxymethylbenzene; (2R)-2-azaniumyl-3-[(2R)-2-azaniumyl-3-oxido-3-oxopropyl]disulfanylpropanoate; (3E)-2-hydroxy-4,8-dimethylnona-3,7-dienal; (2R)-2-azaniumyl-3-[(2S)-2-azaniumyl-3-oxido-3-oxopropyl]disulfanylpropanoate; (3Z)-3-butylidene-2-benzofuran-1-one; 3-methyl-N-(3-methylbutyl)butan-1-imine; 2-(furan-2-ylmethyldisulfanylmethyl)furan; and combinations thereof. Uses thereof and methods of improving the taste of an oral care composition.

Oral care compositions with improved flavor

TREK-1 agonist comprising composition that reduces perceived oral discomfort sensation and a method for measuring TREK-1 potassium channel activation.

Compositions for delivery of oral comfort sensations

A composition with reduced bitterness containing polyquaternium-2, polyquaternium-17, and/or polyquaternium-18.

Compositions with reduced bitter taste perception

A liquid medication with reduced bitterness containing a drug active and polyquaternium-2, polyquaternium-17, and/or polyquaternium-18.

Medication with a reduced bitter taste perception

Compounds and methods for modifying sensory perception associated with transient sensory receptors TRPA1, TRPV1, and TRPA1V1. A method for screening compounds for modulation of TRPA1, TRPV1, and/or TRPA1V1. Compositions comprising TRPA1V1 agonists or antagonists, for modifying sensory perception of the compositions.

Methods and compositions for modifying sensorial perception

An oral care composition with reduced bitterness containing polyquaternium-2, polyquaternium-17, and/or polyquaternium-18.

Oral care compositions with a reduced bitter taste perception

A method to detect bioavailable metal ions from an oral care composition and a method to select for compounds that inhibit the uptake of metal ions into cells.

Growing community of inventors

Liberty Township, OH, United States of America

Yakang Lin