Huawei Technologies Co., Limited

Biocytogen Pharmaceuticals (beijing) Co., Ltd.

Yabo Zhang

Yuelei Shen

Jiawei Yao

Hui Lu

Huizhen Zhao

Lili Liu

Shuwen Huang

Chen Wang

Xiangyu Kong

Yanmiao Wang

The present disclosure relates to genetically modified animals and cells with humanized heavy chain immunoglobulin locus and/or humanized light chain immunoglobulin locus.

Genetically modified non-human animals with humanized immunoglobulin locus

This disclosure relates to genetically modified animals and cells with humanized light chain immunoglobulin locus and/or humanized heavy chain immunoglobulin locus. In one aspect, the endogenous light chain immunoglobulin locus comprises a limit number of human IGKV genes and human IGKJ genes.

Genetically modified non-human animals with common light chain immunoglobulin locus

This application provides a network fault locating method and apparatus in an IP network. In this solution, a router automatically reports status information, and a controller determines, based on the status information, whether a communication path is faulty. If a fault exists, the controller may indicate a router on the communication path to perform fault locating. The fault locating can be completed without waiting for manual intervention, so that operation and maintenance efficiency in the IP network is improved. After completing the fault locating, the router reports location information of a fault point to the controller, and the controller may perform troubleshooting at the fault point, so that the fault can be quickly rectified.

Network fault locating method and apparatus

This application provides a method for constructing a blockchain network based on an interior gateway protocol (IGP). A new IGP packet used to transmit a blockchain task is provided by extending the IGP. When receiving the new IGP packet, a network device can participate in execution of the blockchain task by using its idle computing power. The computing power of the network device is better utilized to construct the blockchain network, avoiding a waste of idle computing power of the network device.

Packet processing method and device designed for blockchain tasks

In a load sharing method and a router device, each of the router devices in a load sharing relationship obtains load sharing information of all downstream router devices that are in a load sharing relationship with the router device, and when determining load sharing information of the router device, the router device determines the load sharing information of the router device according to the load sharing information of all the downstream router devices that are in a load sharing relationship with the router device, so that a disturbance factor of the router device is different from disturbance factors of all the downstream router devices that are in a load sharing relationship with the router device. Therefore, a coupling degree of load sharing information of all the router devices in a load sharing relationship in the network is reduced, and load sharing at all levels is even.

Growing community of inventors

Beijing, China

Yabo Zhang