Academia Sinica

National Taiwan Normal University

Ya-Wen Cheng

Lie-Fen Shyur

Wen-Wan Chao

Hsi-Chun Wang

Methods for preventing and/or reducing side effects of an anti-cancer agent in a subject in need thereof are disclosed. The method comprises administering to the subject, who is under an anti-cancer agent treatment, a composition comprising a therapeutically effective amount of isolated deoxyelephantopin and/or an analog thereof; and a pharmaceutically acceptable carrier.

Use of deoxyelephantopin (DET) and analogues thereof for reducing side effects of an anti-cancer agent

A watermark and a manufacturing method therefor are provided. The watermark has a first region comprising amplitude modulation (AM) halftone dots and a second region comprising frequency modulation (FM) halftone dots, and each of the amplitude modulation halftone dots has ink portions and blank portions, each of which is located between the two ink portions in the same amplitude modulation halftone dot. The ink area percentage of the amplitude modulation halftone dots are dispersed by filling the blank portions into each of the amplitude modulation halftone dots, so that the density calibration of the amplitude modulation halftone dots and frequency modulation halftone dots can be omitted.

Watermark and manufacturing method therefor

Methods for treating melanoma in a subject in need thereof are disclosed. The method comprises administering to the subject a composition comprising a therapeutically effective amount of deoxyelephantopin or an analogue thereof; and a pharmaceutically acceptable carrier. Methods of inhibiting proliferation, migration and/or metastasis of melanoma cells in a subject in need thereof are also disclosed. Also disclosed are methods for reducing side effects of an anti-cancer agent in a subject in need thereof.

Growing community of inventors

Taipei, Taiwan

Ya-Wen Cheng