Arsenal Medical, Inc.

Xuri Yan

Quynh P Pham

Upma Sharma

John Marini

Toby Freyman

Lee A Core

Robert F Mulligan

Abby N Picard

The present invention relates generally to the field of electrospinning. In particular, the present invention relates to an electrospinning device that includes a slit-fixture defined by an elongate aperture disposed between opposing elements of an electrically conductive material. These elements include a variety of patterns/shapes that affect the flow of fluid through the aperture and the electrical field across the aperture.

Patterned slit fixtures and surfaces for high throughput slit-surface electrospinning

The present invention relates generally to the field of electrospun fibers. In particular, the present invention relates to core-sheath fibers and related electrospinning methods. The fibers of the invention comprise poorly water soluble drugs and/or proteins.

Fibers comprising poorly soluble drugs and/or proteins

Systems and methods for electrospinning of core-sheath fibers are provided. The systems and methods achieve optimization of a shear stress that exists at a fluid boundary between core and sheath polymer solutions, by varying certain parameters of an electrospinning apparatus and/or the solutions used therewith.

Process of electrospinning core-sheath fibers

Devices and methods for high-throughput manufacture of concentrically layered nanoscale and microscale fibers by electrospinning are disclosed. The devices include a hollow tube having a lengthwise slit through which a core material can flow, and can be configured to permit introduction of sheath material at multiple sites of Taylor cone formation formation.

Electrospinning process for manufacture of multi-layered structures

Devices and methods for high-throughput manufacture of concentrically layered nanoscale and microscale fibers by electrospinning are disclosed. The devices include a hollow tube having a lengthwise slit through which a core material can flow, and can be configured to permit introduction of sheath material at multiple sites of Taylor cone formation.

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Boston, MA, United States of America

Xuri Yan