Pioneer Hi-bred International, Inc.

Syngenta Participations Ag

The Scripps Research Institute

Triton Algae Innovations, Inc.

Pioneer Hi-bred Int'l Inc.

Xun Wang

Benjamin A Bowen

Jonathan P Duvick

Timothy George Helentjaris

Kanwarpal Singh Dhugga

Tong Zhu

Joyce R Maddox

Tracy A Rood

Joel Kreps

Liang Shi

Jeffrey F Harper

Bi-Yu Li

Steven P Briggs

Jacob T Gilliam

Larry R Beach

Stephen P Mayfield

Hongyu Wang

Susan J Martino-Catt

Paul Budworth

Miller Tran

Bret Cooper

Bin Han

Devon L Brown

Jon Hansen

Sherman (Hur-Song) Chang

Jon Duvick

Kathryn K Lappegard

Michael Mayfield

Beth Ann Rasala

Robert McBride

Oscar Gonzalez

Guangzhou Zou

John Tzu-Yu Chang

Hur-Song Chang

Yiping Fan

Fan Long

Benjamin A Bowne

Provided herein are methods for the production of high density cultures of algae as well as nutritional supplements from such cultures and the use of such cultures to produce therapeutic proteins.

Method for growing algae

Provided herein are methods for the treatment of GI tract diseases and conditions and/or symptoms associated with such diseases and conditions in a mammal. Also provided are preparations and compositions for use in the methods. Also provided are methods of growing and preparingbiomass for administration to a mammal in need of treatment of GI tract diseases and conditions and/or symptoms associated with such diseases and conditions.

Method of treating alimentary canal conditions

The instant invention is directed to a constitutive promoter for use in plants. The plant genus from which the promoter is derived is. The invention encompasses the isolated promoter, expression cassettes comprising said promoter and a heterologous nucleic acid segment, and monocot and dicot plants and plant cells transformed with said expression cassettes.

[object Object]

Clusters of plant genes that are regulated in response to one or more stress conditions are provided, as are isolated plant stress-regulated genes, including portions thereof comprising a coding sequence or a regulatory element, and to consensus sequences comprising a plant stress-regulated regulatory element. In addition, a recombinant polynucleotide, which includes a plant stress-regulated gene, or functional portion thereof, operatively linked to a heterologous nucleotide sequence, is provided, as are transgenic plants, which contain a plant stress-regulated gene or functional portion thereof that was introduced into a progenitor cell of the plant. Also provided are methods of using a plant stress-regulated gene to confer upon a plant a selective advantage to a stress condition, methods of identifying an agent that modulates the activity of a plant stress-regulated regulatory element, and methods of determining whether a plant has been exposed to a stress.

Stress-regulated genes of plants, transgenic plants containing same, and methods of use

Individual probes on micro-arrays are re-scaled and corrected with a set of probe dependent coefficients derived from genomic-DNA hybridization signals. A dynamic range for gDNA binding is determined by measuring a concentration signal curve. Signals for each probe are measured during multiple hybridizations within a linear range. Concentration insensitive probes are then found for two sets of experiments. Probes are discarded based on a threshold compared to their standard deviation divided by their average in each set. The correction coefficients are used to calculate a corrected intensity for each probe. Probes having high uncertainty (0.5 in one embodiment) are discarded. A weighting factor for each probe is determined along with an uncertainty factor. Finally, a call for each gene is made, such as absent, marginal or present.

Probe correction for gene expression level detection

The invention provides isolated cellulose synthase nucleic acids and their encoded proteins. The present invention provides methods and compositions relating to altering cellulose synthase concentration and/or composition of plants. The invention further provides recombinant expression cassettes, host cells, and transgenic plants.

Maize cellulose synthase encoding sequences and uses thereof

The invention provides a method to identify a plurality of plant promoters having specified characteristics and promoters identified by the method. The plant genus from which at least some of the promoters are derived is. Also provided are transgenic plants comprising the genes identified by the methods of the invention.

Cellulose synthase encoding nucleic acids and uses thereof

Maize cellulose synthase encoding nucleic acids and uses thereof

Methods are provided for identifying genetic markers and for determining methylation patterns using restriction endonucleases having degenerate recognition or cleavage sequences.

Method for identification of genetic markers

Maize cellulose synthases encoding nucleic acids and uses thereof

The invention relates to a new method for sequence-specific identification, separation and quantitative measurement of nucleic acid fragments. The invention is based on the use of restriction endonucleases that have degenerate bases in their recognition or cleavage sequence. The method has broad applications, including DNA fingerprinting, differential display of mRNA, mutation and polymorphism identification, diagnosis and drug screening.

Method for identification, separation and quantitative measurement of nucleic acid fragments

The present invention provides methods and compositions relating to altering lignin biosynthesis content and/or composition of plants. The invention provides isolated nucleic acids and their encoded proteins which are involved in lignin biosynthesis. The invention further provides recombinant expression cassettes, host cells, transgenic plants, and antibody compositions.

Genes encoding enzymes for lignin biosynthesis and uses thereof

Growing community of inventors

San Diego, CA, United States of America

Xun Wang