Tsinghua University

Cofco (jilin) Bio-chemical Technology Co., Ltd

Nutrition & Health Research Institute, Cofco Corporation

Cofco Biotechnology Co., Ltd.

Xuemei Shen

Kai Yang

Bo Chen

Wei Lin

Qiong Wu

Xiaoyan Wang

Yi Tong

Kejia Xu

Lida Wu

Tai An

Fang Tian

Chao Peng

Jin Tao

Dayong Li

Haijun Liu

Weiqiang Zhou

Guoqiang Chen

Yuanheng Guo

Anni Liu

A method for efficiently producing PHA comprising: inoculating PHA fermentation strains into a fermentation medium for fermentation under the condition of being capable of producing PHA through fermentation; subjecting the fermentation broth to a solid-liquid separation to obtain fermentation supernatant and thallus precipitate; breaking the cell walls of the thallus precipitate, and subjecting the wall-broken products to a plate and frame filtration to prepare PHA; pre-coating a filter cloth for the plate and frame filtration with a PHA layer; at least part of the water of the fermentation medium is PHA process wastewater. The method utilizes the PHA process wastewater as at least part of the water of the fermentation medium, and filters and separates the broken thallus with the plate and frame filtration equipment pre-coated with PHA layer to prepare PHA, thereby recycling the high-salt wastewater, reducing costs, and potentially separating PHA on a large scale for industrial production.

Method for efficiently producing PHA

Growing community of inventors

Beijing, China

Xuemei Shen