Shanghai Ennovabio Pharmaceuticals Co., Ltd.

Ennovabio (zhejiang) Pharmaceuticals Co., Ltd.

Xueli Xu

Lei Jiang

Yuan Xu

Ke Shang

Jianwen Deng

Haixia Zhao

Shengyang Liu

Xiaoping Xie

Zhi Qiao

Yi Zhang

Zhiyong Feng

Mingwei Zheng

Bing Wang

Jianyong Shou

Danyi Wu

Xiaoli Lu

The present invention provides preparation of a semicarbazide-sensitive amine oxidase inhibitor and use thereof. In particular, disclosed in the present invention are a compound as represented by formula I, or a stereoisomer or a racemate or a pharmaceutically acceptable salt of the compound. Also disclosed in the present invention is that the compound can inhibit semicarbazide-sensitive amine oxidase.

Preparation of semicarbazide-sensitive amine oxidase inhibitor and use thereof

Provided are a preparation of semicarbazide-sensitive amine oxidase inhibitor and the use thereof. In particular, disclosed are a compound as shown in formula I, or a stereoisomer or racemate or pharmaceutically acceptable salt thereof. Also disclosed is that the above-mentioned compound can inhibit semicarbazide-sensitive amine oxidase.

Preparation of seimicarbazide-sensitive amine oxidase inhibitor and use thereof

Provided are a compound for the prevention and treatment of diseases associated with PD-L1, a preparation method therefor and use thereof. Specifically, provided are the compound of formula I, the stereoisomer and the racemate thereof, or pharmaceutically acceptable salts thereof, and also provided is an application thereof in the preparation of a drug for the prevention and treatment of diseases associated with PD-L1.

Compound having PD-L1 inhibitory activity, preparation method therefor and use thereof

Growing community of inventors

Shanghai, China

Xueli Xu