Star Array Pte Ltd

Xudong Zeng

Haiqing Gong

Yan Wen

Thermal cycling apparatus for polymerase chain reaction (PCR) of nucleic acid is provided. Bath media in a first bath and a second bath are maintainable at two different temperatures. A transfer means allows the reactor to be in the two baths in a plurality of thermal cycles to alternately attain a predetermined high target temperature Tand a predetermined low target temperature T. A florescent imaging means images the reaction material during the thermal cycling. A powder-cleaning device mechanically removes particles of powder that adhere to the reactor, when powder is the bath medium in use in at least one of the baths.

Apparatus for polymerase chain reaction of nucleic acid

A method and an apparatus for thermal processing of nucleic acid in a thermal profile. The method employs at least a first bath and a second bath, the method further employing a reactor holder for holding reactor(s) accommodating reaction material containing the nucleic acid. The method includes maintaining bath mediums in the baths at two different temperatures; and alternately allowing the reactor(s) to be in the two baths in a plurality of thermal cycles to alternately attain a predetermined high target temperature T, and a predetermined low target temperature T, wherein the bath medium in at least one of the baths is a high thermal conductivity powder.

Growing community of inventors

Singapore, Singapore

Xudong Zeng