City University of Hong Kong

Xudong Lin

Peng Shi

Xin Wang

Ming Liu

A method for analyzing neuropharmacology of a drug, including the steps of providing a set of brain activity maps representing changes of a brain activity of a living species under an influence of a plurality of known drugs each consisting of a known chemical structure; clustering the set of brain activity maps to form a plurality of functional classifiers; and classifying a brain activity map associated with a chemical compound using the functional classifiers so as to predict a neuropharmacology of the chemical compound.

Method and a system for analyzing neuropharmacology of a drug

A wireless optogenetic device in proximity to a neural cell of a subject includes a body configured to hold light transducing materials arranged to up-convert electromagnetic radiation in infrared or near-infrared spectrum into light in the visible spectrum to affect activity of the neural cell. The body allows electromagnetic radiation in infrared or near-infrared to reach the light transducing materials. A radiation system includes a radiation probe for irradiating a wireless optogenetic device with electromagnetic radiation in infrared or near-infrared spectrum from a radiation source. The system further includes a movement mechanism for moving the radiation probe, a detector for detecting a location of the wireless optogenetic device, and a controller for controlling the movement mechanism based on the detected location of the wireless optogenetic device such that the radiation probe is arranged to irradiate the wireless optogenetic device at the detected location with the electromagnetic radiation.

Wireless optogenetic device and associated radiation system

There is provided a system for automated handling of live organisms for studying biological development of the organisms. The system has a reservoir for containing a plurality of the organisms, a module for automatically trapping and orienting the organisms in desired positions for imaging purpose, a module for automatically controlling orientation of the organisms leaving the reservoir and entering the trapping and orienting module, and a module for automatically loading the organisms from the reservoir into the orientation control module. The trapping and orienting module may include an array of channels configured to allow flow of fluid and travel of the organisms in the system.

Growing community of inventors

Hong Kong, China

Xudong Lin