Medshine Discovery Inc.

Guangzhou Ocusun Ophthalmic Biotechnology Co., Ltd.

Helioeast Science & Technology Co., Ltd.

Jiangsu Zhongtian Technology Co., Ltd.

Jumbo Drug Bank Co., Ltd.

Helioeast Pharmaceutical Co., Ltd.

Ocusun Ophthalmic Pharmaceutical Co., Ltd.

Xu You

Lingyun Wu

Shuhui Chen

Lele Zhao

Jian Li

Xiongbin Xu

Xiawei Wei

Yizhi Liu

Ning Jiang

Yandong Wang

Zheming Xiao

Peng Yang

Hua Zhou

Xinming Du

Jian Ge

Chenshi Wang

Weiwei Miu

Disclosed are an acetophenone oxime compound and a preparation method therefor, and specifically disclosed are a compound as shown in formula (II) and a pharmaceutically acceptable salt thereof.

Acetophenone oxime compound and application thereof

Disclosed are a series of isoquinolone derivatives as ROCK protein kinase inhibitors and uses thereof in preparing medicaments for ROCK protein kinase inhibitor-related glaucoma or ocular hypertension diseases. Specially, disclosed are a compound of formula (I), an isomer thereof or a pharmaceutically acceptable salt thereof.

Isoquinolinone derivatives serving as rock protein kinase inhibitors and use thereof

Disclosed are a series of benzo 2-azaspiro[4.4]nonane compounds, and specifically disclosed are a compound as represented by formula (P) or a pharmaceutically acceptable salt thereof.

Benzo 2-azaspiro[4.4]nonane compound and use thereof

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Shanghai, China

Xu You