University of Shanghai for Science and Technology

Yung Shin Pharmaceutical Ind. Co., Ltd.

Chongqing Institute Forfood and Drug Control

Xu Wu

Yan Peng

Yiming Zhu

Li Zhou

Songlin Zhuang

Fang Yu Lee

Chenjun Shi

Songyan Hu

Xitian Hu

Qingrou Yang

Can Sun

Weinan Ge

Chang An Yang

Linggao Zeng

Fang Chen Lee

Ma Wei Yong

Zefang Wang

Wu Qiu Ye

Xiao Xu Hua

A method for qualitative identification and quantitative determination of caffeine in a drug. In the method, terahertz absorption coefficient spectra of drugs with different concentrations of caffeine are measured, from which the frequency points, amplitudes and peak areas of characteristic peaks of the drugs with different concentrations of caffeine are obtained as characteristic quantities. Concentration gradients are established between the concentrations and the characteristic quantities, respectively. The characteristic quantities are imported to the SVR model to establish a training set and a test set. Finally, the qualitative identification and quantitative analysis of caffeine in unknown drugs are achieved.

Method for qualitative identification and quantitative determination of caffeine in drug

Provided is a method for identifying authenticity and origin ofbased on terahertz spectroscopy. The time domain spectral information of thesample is obtained, and converted into the frequency domain spectral information by Fourier transform to calculate a terahertz absorption spectrum. The identification is performed by observing whether there are characteristic absorption peaks of pseudoginsenoside F11 in the terahertz absorption spectrum.

Method for identifying authenticity and origin ofbased on terahertz spectroscopy

Fused tri-heterocyclic compounds of formula:Ris H or alkyl; Ris H, alkyl, alkenyl, aryl, heteroaryl, cyclyl, or heterocyclyl; Rand R, independently, is H, alkyl, alkenyl, aryl, heteroaryl, cyclyl, heterocyclyl, or (CRR)X(CRR)Y; in which X is a bond, O, S, or NR; Y is alkoxy, aryloxy, heteroaryloxy, OC(O)R, C(O)R, N(RR), NRC(O)R, S(O)R, or SR; each of m and n, independently, is 1, 2, 3, 4, or 5; each of R, R, R, R, R, and R, independently, is H, alkyl, aryl, heteroaryl, cyclyl, or heterocyclyl; and Ris H or halogen.

9H-imidazo[1,2-a]purin-9-one compounds

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Shanghai, China

Xu Wu