Petrochina Company Limited

National Research Institute for Family Planning

Xu Ma

Zhe Li

Wei Gao

Bin He

Xianwen Li

Lei Shen

Yong Ding

Yajuan Wang

Xiaorui Liu

Yun Ling

Zhanguo Ma

Qianyun Zhao

Liangyu Xia

Changjing Zhou

Qiaorong Han

Yuanxiang Xiao

Xinxing Ma

Man Bi

Huaqiang Shi

Hua Shi

Yanming Zhang

Baochun Chen

Mingfang He

Yonghong Gu

Hongying Li

Ruifen Hao

Xiaoyong Wen

Guohui Su

Liang Ye

Shaowei Zhou

Xuan'ang Lai

Shusheng Li

Yangming Hu

Meiying Ning

The present invention relates to a vaginal sustained-release drug delivery system for luteal support and a method for preparation and use thereof. The vaginal sustained-release drug delivery system for luteal support is a progesterone depot-type vaginal ring having a bilayer structure of a core layer and a film layer enclosing the core layer, wherein the core layer is composed of a solid scaffold carrier of medical EVA containing a drug uniformly dispersed therein, and the film layer is composed of a medical EVA material containing no drug. The vaginal sustained-release drug delivery system for luteal support according to the present invention can be used for assisted reproduction and for treatment of functional uterine bleeding, premenstrual syndrome and the like due to luteal phase defect with a significantly improved therapeutic effect.

Vaginal sustained-release drug delivery system for luteal support, method for preparation and use thereof

The present invention discloses a method for lowering an oil pipe in a gas well without well-killing, a soluble bridge plug and a material preparation method thereof, wherein, the method comprises the steps of: lowering a bridge plug in a wellbore such that the bridge plug blocks the wellbore at a predetermined location in the wellbore; injecting water in the wellbore after the pressure in the wellbore has been relieved so as to replace gases in the wellbore; and lowering an oil pipe in the wellbore to the location of the bridge plug. The method for lowering an oil pipe in a gas well without well-killing, the soluble bridge plug and the material preparation method thereof provided in the present invention successfully solve the problem of high cost for lowering an oil pipe under pressure after a fracturing fluid has been injected into the casing.

Method for lowering oil pipe in gas well without well-killing, soluble bridge plug and material preparation method thereof

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Beijing, China

Xu Ma