Zhejiang University

Zhejiang Lab

Xu Liu

Haifeng Li

Cuifang Kuang

Zhenrong Zheng

Xinxing Xia

Weidong Shen

Yueguang Zhang

Chenying Yang

Wentao Zhang

Shaocong Liu

Chenning Tao

Xiao Tao

Caijie Yan

Shuai Li

Yifan Peng

Xiangdong Liu

Yuanfang Lin

Yuran Huang

Bo Fang

Zhimin Zhang

Yusen Zhang

Yuxuan Qiu

Zhenyao Yang

Xiang Hao

Jisen Wen

Hongqing Wang

Zhaotai Gu

Mengbo Tang

Ziang Wang

Lanxin Zhan

Xiaoyi Zhang

Wanjie Dong

A confocal scanning dark field microscopy imaging method and device, comprising: modulating a phase of a laser beam emitted by a laser into a 0-2π π vortex phase, where n>3; conjugating the modulated laser beam with an entrance pupil of an objective lens of a confocal scanning microscope, so that a focusing spot of the objective lens is a hollow spot, and an inner ring radius of the hollow spot is greater than a radius of a solid spot without phase modulation; and enabling the confocal scanning microscope to work, thereby achieving dark field microscopy imaging. The present disclosure adopts a confocal design with a pore placed in front of the detector. The plane of the pore is conjugated with the object plane, blocking a defocusing signal from entering the detector.

Confocal scanning dark field microscopy imaging method and device

A super-resolution microscopic imaging method and apparatus based on common-path parallel fluorescence emission difference microscopy. In the method, a liquid crystal spatial light modulator is used to modulate excitation light in fluorescence emission difference microscopy super-resolution microscopic imaging, and two parts of the spatial light modulator are respectively loaded into 0-2π vortex phase modulation and blazed grating, so that the common-path excitation light forms solid spot and doughnut-shaped spot with a certain distance on a sample surface at the same time, and parallel scanning is carried out, thereby ensuring that the imaging speed is doubled compared with that of ordinary fluorescence emission difference super-resolution microscopic imaging, and at the same time, the two excitation lights are not easily affected by noise, drift and other interferences due to the common path.

Super-resolution microscopic imaging method and apparatus based on common-path parallel fluorescence emission difference microscopy

Disclosed is a phase-modulated fluorescence differential microscopic imaging device based on electro-optical modulation technology, including an illumination system for generating an excitation beam, a detection system for collecting a fluorescent signal emitted by a sample, and a computer for controlling and signal processing. The illumination system includes the following components that are sequentially arranged: a laser, emitting a laser beam; an electro-optical modulation module, configured to control a rapid conversion of the laser beam between a right-handed circularly polarized light and a left-handed circularly polarized light; and a phase modulation device, configured to modulate a circularly polarized light to form a solid light spot and a hollow light spot for illuminating the sample and exciting fluorescence. Also disclosed is a phase-modulated fluorescence differential microscopic imaging method based on the electro-optical modulation technology, which realizes a rapid conversion of a solid light spot and a hollow light spot, and improves the imaging speed of the fluorescence differential microscopic imaging system to a large extent.

Phase-modulated fluorescence differential microscopic imaging method and device based on electro-optical technology

A method and an apparatus for direct writing photoetching by parallel interpenetrating super-resolution high-speed laser. The method of the present application uses a parallel interpenetrating algorithm. Firstly, a multi-beam solid light spot for writing is generated based on a writing light spatial light modulator; a multi-beam hollow light spot for inhibition is generated based on an inhibition optical spatial light modulator; the multi-beam solid light spot is combined with the multi-beam hollow light spot to generate a modulated multi-beam light spot; a writing waveform is output based on a multichannel acousto-optic modulator, a displacement stage moves at a constant speed until writing of a whole column of areas is completed, an optical switch is turned off, and the displacement stage conducts one-time stepping movement; the process is not stopped until all patterns are written.

Method and apparatus for direct writing photoetching by parallel interpenetrating super-resolution high-speed laser

The invention discloses a wide-field multi-scale high-resolution microscopic imaging system, which includes a light source, a sample, a microscope imaging objective system, an acquisition system, and a workstation. The microscope imaging objective system is used for forming an image after a light beam emitted by the light source illuminates the sample. To obtain a wide-field curved image plane, the acquisition system includes an acquisition lens array for subfield acquisition of the curved image plane, and a camera array for secondary imaging. The workstation is used for analyzing the acquired image in overlapping fields of view, and performing image splicing based on the fields of view, to finally obtain a wide-field high-resolution image. Because of the desire for an improvement to an imaging method, this invention realizes multi-scale high-resolution observation from cells, tissues, to organs while ensuring a wide field of view.

Wide-field multi-scale high-resolution microscopic imaging system and method

The present invention discloses a micro-objective lens, comprising the first lens group, the second lens group, the third lens group, the fourth lens group, the fifth lens group, the sixth lens group, the seventh lens group, the eighth lens group, the ninth lens group and the tenth lens group with optical axis arranged in a sequence from the left to the right; the focal length of the first lens group is negative; the second lens group belongs to doublet, in which the focal length of the first and second lens is positive and negative respectively; the focal length of the third lens group is positive; the fourth and fifth lens groups belongs to doublets, in which the focal length of the first and second lens in each group is negative and positive respectively; the focal length of the sixth lens group is positive; the focal length of the seventh and eighth lens groups is negative; the focal length of the ninth and tenth lens groups is positive. The present invention also discloses a high-resolution broadband imaging system with aforesaid micro-objective lens.

Micro-objective lens and high-resolution broadband imaging system with such micro-objective lens

The present invention discloses a visible near-infrared ultra-broadband absorber and its preparation method, comprising a substrate and a five-layer optical film, wherein the bottom film is a bottom metal absorbing layer; a top germanium layer is provided on the top of the bottom metal absorbing layer; and remaining three layers are provided on the top of the top germanium layer with gradually decreasing refractive indexes from the bottom to the top. The present invention is based on the blocking effect of the metal absorbing layer and broadband anti-reflection film stack of the germanium layer, which has realized visible near-infrared ultra-broadband absorption with high efficiency and good angle insensitivity, and has fully surpassed traditional absorbers in terms of performances. Compared with conventional broadband absorbers and artificial electromagnetic absorbers proposed in recent years, the compact multilayer film structure in the present invention is simpler and avoids complicated nano-fabrication techniques. Therefore, it can significantly reduce production cost and shorten the production cycle, and is thus suitable for large-scale mass production.

Visible near-infrared ultra-broadband absorber and its preparation method

The belt ply feeder and a feeding method include: when a belt ply is conveyed to the front end of a conveying forming board, a force is exerted by a perpendicular adjustment device to drive a conveying forming board bracket to swing upward and rotate around a pivot shaft of a rack to positions at which the upper surface of the conveying forming board is tangential to the periphery of a belt ply drum. According to this arrangement, the belt ply is tangential to the belt ply drum all the time and a belt ply is in firm contact with a belt ply drum regardless of the size of the belt ply drum when wrapping the belt ply around the belt ply drum. Accordingly, the quality of tire shaping can be improved.

Incident angle insensitive color filter and its manufacturing method

This invention discloses a super-resolution microscopy method and device, of which the method comprises the following steps: converting laser beam into linearly polarized light after collimation; linearly polarized light is deflected and phase modulated by a spatial light modulator; the deflected beam is focused, collimated and then converted into circularly polarized light for projection on the sample to collect signal light from various scanning points on the sample, and obtaining the first signal light intensity; switching over modulation function to project linearly polarized light modulated by the second phase modulation on the sample to collect signal light from various scanning points on the sample, and obtaining the second signal light intensity; calculating valid signal light intensity to obtain the super-resolution image. This device features in a simple structure and easy operation, which can obtain a super-resolution beyond diffraction limit at a lower luminous power; it is quick in image formation with the frame frequency over 15 frames when the number of scanning points in each image is 512&#xd7;512.

Super-resolution microscopy method and device

This invention discloses a combined-screen-based multi-pitching angle suspended panoramic space 3D display device comprising: a combined deflective diffusing screen, a high speed projector, an image control module, a rotation detecting module, a motor and a drive mechanism. The high speed projector projects the composite images of the 3D objects of different pitching angles and horizontal 360&#xb0; FOV to different areas of the combined deflective diffusing screen. Each area of the combined deflective diffusing screen controls the deflecting angle and the scattering angle in the vertical direction and the diffusing angle in the horizontal direction, ensuring that the eyes of the surrounding viewers of different height levels can see the 3D images corresponding to their respective positions, representing the 3D scene suspended over the combined deflective diffusing screen.

Combined-screen-based multi-pitching angle suspended panoramic space 3D display device

An omnidirectional-view three-dimensional display apparatus comprises a high-frame-rate projector (), a rotatable reflector device and a cylindrical transmissive selective-diffusing screen (). The optical axis of the high-frame-rate projector () is coincident with the rotating axis of the reflector device and the axis of the cylindrical selective-diffusing screen (). The images projected by the high-frame-rate projector () are reflected by the reflector device to form images on the cylindrical transmissive selective-diffusing screen (). The cylindrical transmissive selective-diffusing screen () can control the diffusing angle of the emergence ray, so that the left eye and the right eye of an observer can see a three-dimensional object's images in different view angles to achieve an omnidirectional-view three-dimensional display. The omnidirectional-view three-dimensional display apparatus based on the high-frame-rate projector () enables the eyes of observers to watch images with binocular parallax at different positions, so as to achieve three-dimensional display.

Omnidirectional-view three-dimensional display apparatus

This invention discloses a multi-pitching angle suspended space 3D display device with 360&#xb0; FOV, comprising: a transmitted composite deflective diffusing screen, a high speed projector, an image generator, a detecting module and a rotating drive mechanism. The high speed projector projects the composite images of the 3D objects of different pitching angles and horizontal 360&#xb0; views to the composite deflective diffusing screen that rotates at a high speed. The composite deflective diffusing screen is able to control the vertical deflecting and scattering angles and horizontal diffusing angle for incident rays with different angles, allowing the surrounding viewers at different height levels to see the images corresponding to their viewpoints, making the displayed 3D objects suspended over the composite deflecting scattering screen, of which the position does not change as the height of the viewpoint changes. The multi-pitching angle suspended space 3D display device with 360&#xb0; FOV allows watching by multiple persons at multiple pitching angles and horizontal 360&#xb0; FOV in naked eyes, realizing space occlusion, exploration and interaction.

Multi-pitching angle suspended 3D display device with 360-degree field of view

A screen device for three-dimensional display with full viewing-field comprises a display screen (), a rotation device () for the display screen, and an optical device () disposed in front side of the display screen (). The optical device () may be a two dimensional diaphragm array () with inclined openings, a vertical lenticular lens array (), a combination of a two dimensional diaphragm array () with vertical openings and a lens (), or a combination of a two dimensional micro-lens array (), a vertical diffusion screen () and a cylindrical lens ().

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Hangzhou, China

Xu Liu