Shanghai Techwell Biopharmaceutical Co., Ltd.

Xiusheng Wang

Xiaoming Ji

Shidong Liu

Zhijun Tang

Zhaoli Zhang

Xiao Xun Zhang

Yi Chen

Xiao Zhang

Jicheng Hu

Liangliang Zhou

Provided in the invention is a solvate of a cyclic peptide compound, represented by formula I is the structural formula of the cyclic peptide compound, and, also disclosed are a preparation method for same and uses thereof. 

Solvate of cyclic peptide compound, preparation method for same, and uses thereof

Disclosed is a novel polymorph of a cyclic peptide compound, the structure whereof is represented by formula I; also disclosed are a preparation method for same and uses thereof. 

Crystal of cyclic peptide compound, preparation method for same and uses thereof

Disclosed is a crystalline powder of a cyclic peptide compound, represented by formula I is the structure of same, and, also disclosed are a preparation method for same and uses thereof. 

Crystalline powder of cyclic peptide compound, preparation method for same, and uses thereof

A high purity cyclopeptide crystal has a structure shown by Formula I. R represents H or a cation forming a pharmaceutically acceptable salt. Also disclosed are a preparation method and a use of the high-purity cyclopeptide crystal. 

High-purity cyclopeptide crystal as well as preparation method and use thereof

Provided is a method for preparing a compound represented by Formula I or a salt thereof, whereinF-11899 (FERM BP2635) and/or a mutant strain thereof is cultured in a medium containing amino acid or a salt thereof, an insoluble organic source, and a sugar alcohol, to produce the compound of Formula I or a salt thereof. 

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Shanghai, China

Xiusheng Wang