The University of Texas System

University of Illinois

Xiumei Huang

Paul Joseph Hergenrother

Jinming Gao

David A Boothman

Joseph S Bair

Elizabeth I Parkinson

Xinpeng Ma

Lifen Cao

Xiuquan Luo

Zachary R Moore

Jimming Gao

Paul J Hergenrother

The therapies described herein can be selectively lethal toward a variety of different cancer cell types and cancer conditions in a subject. The combination therapies described herein can be useful for the management, treatment, control, or adjunct treatment of diseases, where the selective legality is beneficial in chemotherapeutic therapy, particularly where the disease is accompanied by elevated levels of NQO1.

Tumor-selective combination therapy

The therapies described herein can be selectively lethal toward a variety of different cancer cell types and cancer conditions in a subject. The combination therapies described herein can be useful for the management, treatment, control, or adjunct treatment of diseases, where the selective lethality is beneficial in chemotherapeutic therapy, particularly where the disease is accompanied by elevated levels of NQO1.

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Dallas, TX, United States of America

Xiumei Huang