China University of Petroleum

Guangzhou Hc Pharmaceutical Co. Ltd

Institute of Medicinal Biotechnology, Chinese Academy of Medical

Xiukun Wang

Wei Liu

Qi Wang

Yang Song

Bin Huang

Xi Lu

Jin Chen

Sheng Tang

Xuefu You

Lifeng Chen

Yinghong Li

Cheng Fu

Xinxuan Qi

Kaoping Song

Daigang Wang

Danqing Song

Xinxin Hu

Yanxiang Wang

Zhihao Guo

Zhiwen Li

The present invention relates to a compound as shown in general formula (I) below (in formula (I), each of Rand Rindependently represents a hydrogen atom or a C1-10 linear or branched alkyl optionally having a substituent, or the two together form a cycloalkyl with 3 to 8 ring carbon atoms; each of Rand Rindependently represents a hydrogen atom or a C1-10 linear or branched alkyl optionally having a substituent or a C6-12 aryl optionally having a substituent, or the two together form a cycloalkyl with 3 to 8 ring carbon atoms; X represents C or N; and Y represents a linear or branched alkenyl or alkynyl with 2 to 6 carbon atoms and optionally having a substituent, or carboxyl). The compound has good antibacterial properties against bacteria, especially gram-negative bacteria, has low drug resistance, and has good prospects for the effective treatment of various conditions.

β-lactam compound, use thereof and preparation method therefor

The present application provides a method and device for data-driven fracture-cavity reservoir development and evaluation and a storage medium. The method includes: obtaining a fracture-cavity spatial topological relationship, a geometric shape and a fracture-cavity physical model of fault-controlled fractures and cavities, and establishing a first fault-controlled fracture-cavity reservoir discrete spatial topological network model corresponding to the fault-controlled fractures and cavities according to the fracture-cavity spatial topological relationship and geometric shape; performing, according to the first fault-controlled fracture-cavity reservoir discrete spatial topological network model, modeling processing on quantitative representation of production performance of a fault-controlled fracture-cavity reservoir using fluid vertical equilibrium mechanism and non-Darcy flow law, to form a quantitative representation model of production performance of fault-controlled fracture-cavity reservoir; performing analyzing processing on the quantitative representation model to obtain a development performance characteristic of the fault-controlled fracture-cavity reservoir, and developing the fault-controlled fracture-cavity reservoir according to the development performance characteristic.

Method and device for data-driven fracture-cavity reservoir development and evaluation, and storage medium

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Beijing, China

Xiukun Wang