Life Technologies Corporation

Thermo Fisher Scientific Geneart Gmbh

Life Technologies As

Invitrogen Dynal As

University of Southern Denmark

Xiquan Liang

Geir Fonnum

Robert Jason Potter

Mahbod Hajivandi

Namritha Ravinder

Xavier De Mollerat Du Jeu

Todd Peterson

Frank Notka

Thomas Poehmerer

Axel Trefzer

Kristian Andersson

John Leite

Robert Marshall Pope

Korbinian Heil

Xin Yu

Federico Katzen

Torkel Stene

Stine Bergholtz

Yizhu Guo

Phillip Kuhn

Sanjay Kumar

Martin R Larsen

Ole N Jensen

Finn Kirpekar

Kasper Engholm-Keller

Nini Hofsloekken Kjus

Andreas Zeidler

Robert Potter

Chang-Ho Baek

Lansha Peng

Shantanu Kumar

Ansgar Romig

Provided herein are compositions and methods useful, inter alia, for the delivery of ribonucleoprotein complexes (e.g., Cas9/guide RNA complexes) into cells. The compositions and methods provided herein are particularly useful for the delivery of ribonucleoprotein complexes into pluripotent cells and lymphatic cells.

Ribonucleoprotein transfection agents

The invention provides methods for quantifying biomolecules, such as polypeptides in mass spectrometric analysis. The methods include use of a biomolecule standard having at least one atomic isotope different than that of the naturally occurring isotopes in the biomolecule of interest. Methods of the present invention also include methods for quantifying biomolecules where the copy biomolecule standard is made by expressing the biomolecule using a recombinant cell. Further included are the biomolecule standards themselves, method for making such standards, kits, systems, reagents, and engineered cells relating to the use of biomolecule standards in mass spectrometric analysis.

Isotopically-labeled proteome standards

The disclosure generally relates to compositions and methods for the production of nucleic acid molecules. In some aspects, the invention allows for the microscale generation of nucleic acid molecules, optionally followed by assembly of these nucleic acid molecules into larger molecules. In some aspects, the invention allows for efficient production of nucleic acid molecules (e.g., large nucleic acid molecules such as genomes).

High efficiency, small volume nucleic acid synthesis

The present disclosure generally relates to compositions and methods for improving the efficiency of homologous recombination. In particular, the disclosure relates to reagents and the use of such reagents.

Compositions and methods for enhancing homologous recombination

The present disclosure generally relates to compositions and methods for the genetic modification of cells. In particular, the disclosure relates to CRISPR reagents and the use of such reagents.

CRISPR oligonucleotides and gene editing

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Escondido, CA, United States of America

Xiquan Liang