Beijing Ql Biopharmaceutical Co., Ltd.

Northeast Agricultural University

Xinyu Zhao

Xu Chen

Wei Guo

Yuanyuan Zhang

Peng Zhai

Haixia Zou

Yaoguang Jin

Beidou Xi

Mingxiao Li

Liming Jia

Tianxue Yang

Zimin Wei

Xu Zhang

Bo Wu

Lingli Zeng

Xinle Wu

Dan Wei

Zuobin Wang

Baiyan Cai

Yue Zhao

Yuanfeng Li

Tiejun Wen

The present disclosure provides fusion polypeptides comprising serum albumin binding single domain antibody and GDF15, the polypeptide complexes thereof. Pharmaceutical compositions comprising the same and methods of treating diseases are also provided.

Fusion proteins of GDF15 and use thereof

The present disclosure provides a polypeptide conjugates comprising GLP-1 receptor agonist and a peptide linker, and pharmaceutical compositions comprising the same. Methods of using such for treating diseases are also provided.

Polypeptide conjugates and methods of uses

The present disclosure provides fusion polypeptides comprising GLP-1 and GDF15, the polypeptide complexes, and the conjugates thereof. Pharmaceutical compositions comprising the same and methods of treating diseases are also provided.

Fusion proteins of GLP-1 and GDF15 and conjugates thereof

The present invention provides a vertical gas distribution device for aerobic compost and a gas distribution method. Current gas distribution pipelines are easily blocked by organic materials, resulting in poor ventilation due to non-uniform local ventilation and cleaning difficulties. The inventive device comprises a compost chamber, a compost bin, a compost heap, a percolate tank, and a plurality of gas distribution branch pipes at the bottom of the compost chamber, the pipes being vertically movable in the chamber; the percolate tank is positioned at the bottom of the chamber and under the pipes; an air inlet is provided on the side wall of the tank, and an outlet is provided on the side wall of the chamber; the compost bin is inside the compost chamber, and the compost heap is in the compost bin; each pipe is top sealed, with a plurality of vent holes on the side wall, and its bottom connected to the tank. The present invention is usable for compost ventilation.

Vertical gas distribution device for aerobic compost and gas distribution method

The present disclosure relates to a device and method for remedying a heavy-metal-polluted soil with a microorganism, and relates to a device for remedying a metal-polluted soil and a remediation method thereof. The present disclosure solves the problem that a remediation microorganism cannot be extracted from the soil. The device comprises a main plate and a plurality of microorganism-extracting chambers, wherein the main plate is connected to the microorganism-extracting chambers; the microorganism-extracting chamber are filled with a filler; a tail end of the microorganism-extracting chambers is spiky, and openings are separately provided on a side wall of the microorganism-extracting chambers. The method comprises: I, adding a nutrient medium to the soil, and then inoculating a remediation microorganism; and II, inserting the above device into the soil for 6&#x2dc;8 days, and then taking it out. The method can remedy heavy-metal-polluted soil in a short time with a high removal rate of the heavy metal.

Device and method for remedying heavy-metal-polluted soil with microorganism

Growing community of inventors

Beijing, China

Xinyu Zhao