Jiangnan University

Xinyu Meng

Yun Fang

Yongmei Xia

Xiang Liu

Xueyi Hu

Ye Fan

Conglin Ren

Huan Liu

Fei Qian

Jie Shen

Yitao Hu

The present disclosure discloses a preparation method of fatty acid-based VC liposomes, and belongs to the field of pharmaceutical preparations. In the disclosure, a complex of industrial conjugated linoleic acid and other fatty acids with sodium dodecyl sulfate is taken as a capsule material, which is self-assembled to embed vitamin C in an aqueous phase under an acidic condition (pH<7) to form the fatty acid-based vitamin C liposome. The preparation method of the disclosure does not use organic solvents and other substances harmful to the human body, and has the characteristics of safety and health. In addition to VC encapsulation under the acidic condition, the prepared fatty acid-based liposome can play a role in slowly releasing VC.

Preparation method of fatty acid liposome for VC encapsulation

The disclosure discloses preparation and application of an alkylcyclohexanol polyoxyethylene ether emulsifier, and belongs to the technical field of surfactants. By performing ethylene oxide adducting on alkylcyclohexanol polyoxyethylene ether (1-3) and using a strong alkaline suspension dispersed in the solvent and alkylcyclohexanol polyoxyethylene ether (1-3) as a catalyst, nonionic surfactants alkylcyclohexanol polyoxyethylene ether (5-17) are synthesized. The products all have good characteristics of nonionic surfactants, and contain lower content of polyethylene. The products such as nonylcyclohexanol ethoxylate (7) and nonylcyclohexanol ethoxylate (9) have emulsifying properties similar to the emulsifying property of nonylphenol ethoxylate (10), and therefore can substitute for nonylphenol ethoxylate (10) as an emulsifier.

Preparation of alkylcyclohexanol polyoxyethylene ether emulsifier and application thereof

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Wuxi, China

Xinyu Meng