Ethicon, Gmbh

Cilag International Gmbh

Ethicon Endo-Surgery, Inc.

Johnson & Johnson Consumer Companies, Inc.

Xintian Ming

Frederick E Shelton, IV

Thomas W Huitema

Stephen J Rothenburger

Tamara S Widenhouse

Yi-Lan Wang

Robert W Van Holten

Leo B Kriksunov

Ying Sun

Jue-Chen Liu

Michael D Southall

Joerg Priewe

Jerome Riebman

Jerry Y Jonn

Howard Scalzo

Robert C Di Luccio

Jerome A Fischer

Michael Hamilton

Henry Pokropinski, Jr

James E Hauschild

Hongbo Liu

Frank Cichocki

Jeannette Chantalat

Modesto Eemeta

Michael (Jake) Hamilton

Huimin Wang

Howard Scalzo, Jr

Henry Pokropinski

Stephen Rothenburger

Michael (jake) Hamilton

Methods and devices are provided for promoting wound healing. In general, surgical staplers and stapler components are provided having a coating thereon that is configured to selectively control an interaction between at least one matrix metalloproteinase (MMP) inhibitor and an outer surface of the stapler or stapler component.

Surgical stapler with end effector coating

A disposable dressing forms a compartment around and above a wound site and a volatile antimicrobial compound is allowed to sublimate/evaporate into the compartment. A heating element is included in the dressing, with heat stimulating wound healing and simultaneously accelerating sublimation/evaporation of the antimicrobial compound.

Wound treatment system

A staple cartridge assembly for use with a surgical stapler. The assembly has a cartridge body having a support portion with a plurality of staple cavities with openings. There is also a plurality of staples, wherein at least a portion of each the staple is removably stored within a staple cavity. Each the staple is movable between an unfired position and a fired position, and is deformable between an unfired configuration and a fired configuration. The assembly also includes a compressible tissue thickness compensator configured to be captured within the staples. The compressible tissue thickness compensator at least partially covers the staple cavity openings. The compressed tissue thickness compensator is configured to assume different compressed heights within different staples. The compressible tissue thickness compensator comprising a lyophilized foam having an anti-microbial agent embedded therein.

Tissue stapler having a thickness compensator

The invention relates to a transparent, absorbent device for the dressing of wounds and insertion sites of percutaneous and drug delivery devices. The device provides 360 degree or complete circumferential protection of a wound or insertion site of a percutaneous or drug delivery device and comprises a hydrogel center and at least one absorbent material. The hydrogel center can optionally comprise a bioactive agent(s).

Dressing device

A staple cartridge assembly for use with a surgical stapler. The assembly has a cartridge body having a support portion with a plurality of staple cavities with openings. There is also a plurality of staples, wherein at least a portion of each the staple is removably stored within a staple cavity. Each the staple is movable between an unfired position and a fired position, and is deformable between an unfired configuration and a fired configuration. The assembly also includes a compressible tissue thickness compensator configured to be captured within the staples. The compressible tissue thickness compensator at least partially covers the staple cavity openings. The compressed tissue thickness compensator is configured to assume different compressed heights within different the staples. The compressible tissue thickness compensator comprising a lyophilized foam having an anti-microbial agent embedded therein.

Tissue stapler having an anti-microbial agent

The present invention relates generally to agents and devices for promoting hemostasis and, more particularly, to an extract of a plant-based 'Traditional Chinese Medicinal' product and devices incorporating such agents for the delivery thereof to bleeding wounds.

Hemostatic preparation containing an extract of golden moss

A staple cartridge assembly for use with a surgical stapler. The assembly has a cartridge body having a support portion with a plurality of staple cavities with openings. There is also a plurality of staples, wherein at least a portion of each the staple is removably stored within a the staple cavity. Each the staple is movable between an unfired position and a fired position, and is deformable between an unfired configuration and a fired configuration. The assembly also includes a compressible tissue thickness compensator configured to be captured within the staples. The compressible tissue thickness compensator at least partially covers the staple cavity openings. The compressed tissue thickness compensator is configured to assume different compressed heights within different the staples. The compressible tissue thickness compensator comprising a lyophilized foam having an anti-microbial agent embedded therein.

Tissue stapler having a thickness compensator incorporating an anti-microbial agent

Novel antimicrobial compositions and coatings are disclosed. The antimicrobial compositions consist of mixtures of taurolidine and protamine, including protamine salts. The antimicrobial compositions are particularly useful in coatings for implantable medical devices. The antimicrobial compositions are effective against a broad spectrum of microbes.

Broad-spectrum antimicrobial compositions based on combinations of taurolidine and protamine and medical devices containing such compositions

An antimicrobial composition comprising: a complex of an anionic polyester with an antimicrobial cationic surfactant, wherein the anionic polyester has at least one carboxylic group. A medical device having an antimicrobial composition comprising: a complex of an anionic polyester with an antimicrobial cationic surfactant wherein the anionic polyester has at least one carboxylic group.

Antimicrobial polymer compositions and the use thereof

A medical device having an antimicrobial coating. The device has a first coating layer having an antimicrobial agent over at least part of the outer surfaces of the device. The first coating has an outer surface. There is a second discontinuous polymeric coating containing an antimicrobial agent, which is on top of and covering part of the outer surface of the first coating. The second discontinuous coating has a microstructure.

Antimicrobial coatings with preferred microstructure for medical devices

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Bridgewater, NJ, United States of America

Xintian Ming