Suzhou Rainmed Medical Technology Co., Ltd.

Xingyun Wu

Guangzhi Liu

Yunfei Huo

Zhiyuan Wang

A method for calculating coronary artery fractional flow reserve includes determining myocardial volume by extracting myocardial images; locating a coronary artery inlet and accurately segmenting coronary arteries; generating a grid model required for calculation by edge detection of coronary artery volume data; determining myocardial blood flow in a rest state and CFR by non-invasive measurement; calculating the total flow at the coronary artery inlet in a maximum hyperemia state; determining the flow in different blood vessels in the coronary artery tree in the maximum hyperemia state and then determining flow velocity Vin the maximum hyperemia state; using Vas the flow velocity at the coronary artery inlet and calculating a pressure drop ΔP from the coronary artery inlet to a distal end of a coronary stenosis, and a mean intracoronary pressure Pd at the distal end of the stenosis P=P−ΔP, and calculating fractional flow reserve.

Method for calculating coronary artery fractional flow reserve on basis of myocardial blood flow and CT images

A method for calculating an index of microcirculatory resistance includes determining myocardial volume by extracting myocardial images; locating a coronary artery inlet and accurately segmenting coronary arteries; generating a grid model required for calculation; determining myocardial blood flow in a rest state and CFR; calculating total flow at the coronary artery inlet in a maximum hyperemia state; determining flow in different blood vessels in a coronary artery tree in the maximum hyperemia state and then determining a flow velocity Vin the maximum hyperemia state; obtaining the average conduction time in the maximum hyperemia state Tmn, and calculating a pressure drop ΔP from the coronary artery inlet to a distal end of a coronary artery stenosis, and a mean intracoronary pressure Pat the distal end of the stenosis P=P−ΔP, and calculating the index of microcirculatory resistance.

Method for calculating index of microcirculatory resistance based on myocardial blood flow and CT image

Disclosed is a method for calculating fractional flow reserve, comprising: collecting a pressure at the coronary artery inlet of heart by a blood pressure sensor in real-time, and storing a pressure value in a data linked table; obtaining an angiographic time according to the angiographic image, finding out the corresponding data from data queues based on time index using the angiographic time as an index value, screening out stable pressure waveforms during multiple cycles, and obtaining an average pressure Pa; and obtaining a length of the segment of blood vessel from angiographic images of the two body positions, and obtaining a blood flow velocity V; calculating a pressure drop &#x394;P for the segment of the blood vessel using the blood flow velocity V at the coronary artery inlet, and calculating a pressure Pd at the distal end of the blood vessel, and further calculating the angiographic fractional flow reserve.

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Suzhou, China

Xingyun Wu