Nanchang Hangkong University

Xingdao He

Jiulin Shi

Jin Xu

Gang Shi

Yubao Zhang

Zhongqi Hao

Wei Luo

Bin Liu

Shengpeng Wan

Qiang Wu

Mingxuan Liu

Xin Lan

Liangya Cui

Juan Liu

Tianchi Sun

Disclosed is a linear array scanning Brillouin scattering elastic imaging device. In the device, a signal generating system consists of a narrow linewidth continuous wave laser, a half-wave plate, a beam expander, a Y-direction scanning galvanometer, a microlens array, a pinhole array filter, a first plano-convex lens, a polarization beam splitter, a quarter-wave plate and a microscope objective. A signal receiving system consists of a microscope objective, a quarter-wave plate, a polarization beam splitter and an eight-channel optical collimator array. Each channel of an eight-channel spectrometer consists of an optical collimator, a convex lens, a scanning Fabry-Perot interferometer, a photomultiplier tube and an eight-channel photon collection card.

Linear array scanning brillouin scattering elastic imaging device

Disclosed is a Brillouin-optical coherence-speckle based multi-mode elasticity measurement device, including a Brillouin-optical coherence elastography common-path scanning unit, a Brillouin scattering elastography system, an optical coherence elastography system, a speckle elastography system, and a time sequence controller, where the Brillouin scattering elastography system and the optical coherence elastography system share the Brillouin-optical coherence elastography common-path scanning unit. According to the present invention, advantages that Brillouin scattering elastography can perform high-precision measurement on a bulk elasticity modulus, optical coherence elastography can rapidly obtain an elasticity distribution of an entire sample to perform three-dimensional elasticity mapping, and laser speckle elastography can perform wide-field elasticity measurement are utilized to perform in-situ synchronous imaging on elasticity distribution of lesion tissue, so that scientific basis and technical support are provided for early diagnosis of clinical diseases.

Brillouin-optical coherence-speckle based multi-mode elasticity measurement device

Disclosed is a Brillouin-optical coherence tomography angiography (OCTA)-speckle multi-mode elastography system device, including a Brillouin-OCTA sample scanning unit, a Brillouin scattering elastography system, an OCTA system, a speckle detection system, and a time sequence controller. According to the present invention, advantages that the Brillouin scattering elastography system can perform high-resolution measurement on a bulk elasticity modulus, the OCTA system can perform high-resolution structure imaging, and the speckle detection system can perform wide-field blood flow velocity measurement are utilized to perform in-situ synchronous imaging on a blood vessel structure and elasticity distribution, and to quantify a blood flow velocity, so that scientific basis and technical support are provided for early diagnoses of clinical blood vessel diseases.

Brillouin-octa-speckle multi-mode elastography system device

The present invention provides a tapered side-polished fiber-optic biosensor (FOBS) and a method for preparing a tapered side-polished fiber (SPF). The biosensor includes a broadband light source, a first single-mode fiber, a tapered SPF, a second single-mode fiber, and a spectrometer. The broadband light source is connected to the tapered SPF through the first single-mode fiber, and the tapered SPF is connected to the spectrometer through the second single-mode fiber. The broadband light source is configured to emit a light wave. The spectrometer is configured to display a spectrum corresponding to a light wave passing through the first single-mode fiber, the tapered SPF, and the second single-mode fiber successively. In the present invention, a fiber side-polishing technology is combined with a fiber tapering technology to construct a tapered SPF, and a spectrum changes by changing a refractive index around a side-polished tapered region, thereby measuring the refractive index. In addition, the tapered SPF provided in the present invention can generate a Vernier effect, thereby improving the sensor's anti-electromagnetic interference and sensitivity to refractive index measurement.

Tapered side-polished fiber-optic biosensor and method for preparing tapered side-polished fiber

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Nanchang, China

Xingdao He