Coopervision International Holding Company, LP

Coopervision International Limited

Xinfeng Shi

Paul Richardson

Nancy J Keir

James Mun

Arthur Back

Charlie Chen

Yuwen Liu

Ying Zheng

Ye Hong

Charles A Francis

Li Yao

Ronghua Liu

A wettable silicone hydrogel contact lens having a low ionoflux and low evaporation is manufactured by curing a silicone hydrogel polymerizable composition in a contact lens mold comprising front and back lens-forming surfaces, where one of the lens-forming surfaces has a higher polarity than the other lens-forming surface.

Method of manufacturing silicone hydrogel contact lenses having reduced rates of evaporation

Silicone hydrogel contact lenses having ophthalmically acceptable levels of energy loss are described. The lenses are derived from a polymerizable composition including a first siloxane monomer represented by formula (1): wherein m of formula (1) represents one integer from 3 to 10, n of formula (1) represents one integer from 1 to 10, Rof formula (1) is an alkyl group having from 1 to 4 carbon atoms, and each Rof formula (1) is independently either a hydrogen atom or a methyl group; the lenses also include units derived from a second siloxane monomer which is a dual-end methacrylate end-capped polydimethylsiloxane having a number average molecular weight of at least 7,000 daltons. The average energy loss of the silicone hydrogel contact lenses is from about 30% to about 45% when the lenses are fully hydrated. Batches of silicone hydrogel contact lenses and methods of making silicone hydrogel contact lenses are also described.

Silicone hydrogel contact lenses having acceptable levels of energy loss

Silicone hydrogel contact lenses having ophthalmically acceptable levels of energy loss are described. The lenses are derived from a polymerizable composition including a first siloxane monomer represented by formula (1): wherein m of formula (1) represents one integer from 3 to 10, n of formula (1) represents one integer from 1 to 10, Rof formula (1) is an alkyl group having from 1 to 4 carbon atoms, and each Rof formula (1) is independently either a hydrogen atom or a methyl group; the lenses also include units derived from a second siloxane monomer which is a dual-end methacrylate end-capped polydimethylsiloxane having a number average molecular weight of at least 7,000 daltons. Batches of silicone hydrogel contact lenses and methods of making silicone hydrogel contact lenses are also described.

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Fremont, CA, United States of America

Xinfeng Shi