Other

Genepharm, Inc.

University of Pittsburgh

University of Medicine and Dentistry of New Jersey

Corthera Inc.

Xinfan Huang

Elaine Unemori

Martyn A Lewis

Kirk P Conrad

Hanafi Tanojo

Guan-Wei He

Carol A Tozzi

Elaine N Unemori

Martyn Lewis

A method of forming a membrane on a patch of skin using a gel, for the purpose of protecting the skin area or administering pharmacologically active substances to or through the skin area. The main ingredients of the gel are an alkyl acrylate crosspolymer such as Carbopol Ultrez 20 and a water soluble polymer such as polyvinylpyrrolidone (PVP). The gel may also contain other ingredients such as water, ethanol, antioxidants, lubricants, and neutralizers. The gel has the properties of being colorless and clear, low skin and nose irritability, easy to administer, fast membrane forming time, and removable by washing with water.

Compositions and methods for forming protective or therapeutic skin membranes

Compositions, kits and methods are provided for restoring skin barrier function to skin exposed to environmental elements and/or in a pathological condition. In general, divalent cations such as calcium ions and/or magnesium ions are included in a physiologically acceptable medium. In some embodiments, divalent cations are balanced with monovalent cations such as sodium and potassium ions at appropriate ratios in order to maintain the homeostasis of skin barrier. The compositions, kits and methods can be used as cosmetics, cosmeceuticals or pharmaceuticals for improving skin condition, and preventing or treating dermatological diseases and skin disorders.

Cosmetic and cosmeceutical compositions for restoration of skin barrier function

The invention related to methods of treating disease related to vasoconstriction that is a major factor in hypertensive vascular diseases and vasodilation, generally comprising administering to an individual an effective amount of a pharmaceutically active relaxin. Relaxin functions to increase both vasodilation and angiogenesis in males as well as females, and is useful in treating a wide variety of diseases relating to vasoconstriction.

Use of relaxin treat diseases related to vasoconstriction

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Menlo Park, CA, United States of America

Xinfan Huang