Life Technologies Corporation

Xin Wang

Yi-Zhen Hu

Kyle R Gee

Robert Aggeler

Aimei Chen

Hee Chol Kang

Eric Welch

Yexin Wu

Adam York

Quentin Low

Aleksey Rukavishnikov

Jongtae Yang

Water-soluble, fluorescent particles and compositions, kits, and methods of making and using such particles are disclosed. Processes for preparing fluorescent particles and for controlling the size, polydispersity and optical properties of such particles also are provided.

Fluorescent particles

Silicon-substituted rhodamine compounds are disclosed herein. Also described herein are SiR dyes comprising at least one vinyl group attached to the Si atom (10 position) of the SiR dye. Derivatives, functionalized versions, conjugates, kits, related synthetic methods and uses of SiR compounds also are provided. Silicon-rhodamine (SiR) dyes can provide bright fluorescence at far red wavelengths and exhibit good photostability. The compounds described herein can be useful for fluorescent labeling and detection of biological samples.

Silicon-substituted rhodamine dyes and dye conjugates

Water-soluble, conjugated polymers containing one or more dibenzosilole monomer residues, as well as compositions, kits, and methods of making and using such polymers are disclosed. Also disclosed are dibenzosilole derivatives substituted with one or more water-solubilizing groups, and methods of making and using such derivatives to prepare water-soluble dibenzosilole polymers.

Dibenzosilole monomers and polymers and methods for their preparation and use

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Eugene, OR, United States of America

Xin Wang