Affymetrix, Inc.

Panomics, Inc.

Incyte Corporation

Xin Jiang

Xianqiang Li

Henry Yue

Phillip R Hawkins

Mariah R Baughn

April J A Hafalia

Anita Swarnakar

Narinder K Chawla

Shanya D Becha

Reena Khare

Soo Yeun Lee

Thomas W Richardson

Jayalaxmi Ramkumar

Pei Jin

Uyen K Tran

Joseph P Marquis

Ann E Gorvad

Amy E Kable

David Chien

Alan A Jackson

Sean A Bulloch

Patricia M Lehr-Mason

A method is provided for identifying complexes between a transcription factor and another protein, the method comprising: isolating from a biological sample transcription factor complexes based on whether the transcription factor complexes comprise a particular type of transcription factor; and identifying which of a plurality of different proteins are present in the isolated transcription factor complexes.

Method for detecting transcription factor-protein interactions

A method is provided for screening for agents that affect protein degradation rates, the method comprising: taking a library of cells, the cells expressing a fusion protein comprising a reporter protein and a protein encoded by a sequence from a cDNA library derived from a sample of cells, the sequence from the cDNA library varying within the cell library; contacting the library of cells with a plurality of agents which may affect protein degradation rates; for each agent, selecting cells in the library which express short-lived proteins based on whether the cells have different reporter signal intensities than other cells in the library, the difference being indicative of the selected cells expressing shorter lived fusion proteins than the fusion proteins expressed by the other cells in the library; and characterizing the fusion proteins expressed by the selected cells for each agent.

Screening methods involving the detection of short-lived proteins

Various embodiments of the invention provide human receptors and membrane-associated proteins (REMAP) and Q polynucleotides which identify and encode REMAP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of REMAP.

CD40-related receptor that binds CD40L

Growing community of inventors

Saratoga, CA, United States of America

Xin Jiang