Medtronic Minimed, Inc.

Xin Heng

Akhil Srinivasan

Melissa Tsang

Mohsen Askarinya

Chi-En Lin

Zhenzhong Sun

Michael E Miller

Ellis Garai

Sarnath Chattaraj

Poonam S Gulati

Guangping Zhang

Ashwin K Rao

David Probst

Tyler R Wong

Luis A Torres

Rui Kong

Quyen Ong

Inthirai Somasuntharam

Michael N Missaghi

Steven Lai

Sadaf S Seleh

Robert Mckinlay

Bradley Petkus

Ariel Reider

Carlos E Maldonado

Riley Clayton Kimball

Wally Dong

Brennan Toshner

Soroush Hossein Yazdi

Vu Nguyen

The invention provides amperometric analyte sensor systems comprising one or more electrodes designed to monitor in vivo levels of 3-hydroxybutyrate (and optionally glucose as well) in order to facilitate the management of diabetic ketoacidosis. The invention further includes compositions, elements and methods useful with such amperometric analyte sensor systems.

Sensors for 3-hydroxybutyrate detection

A method of testing one or more analyte sensors each comprising a first electrode; a second electrode; and a material layer disposed on or above the first electrode; the method including (a) applying a voltage potential to the first electrode with respect to the second electrode; (b) measuring a test signal comprising an output current from the first electrode that results from the application of the voltage potential; (c) using the test signal from (b) to observe an electrical characteristic of the analyte sensor; and (d) correlating the electrical characteristic a parameter associated with an electrochemical response of the analyte sensor to an analyte, wherein the testing is under dry conditions without exposure of the electrodes to a fluid containing the analyte or an in-vivo environment containing the analyte.

Dry electrochemical impedance spectroscopy metrology for conductive chemical layers

Methods, systems, and devices for continuous glucose monitoring. More particularly, the methods, systems, and devices describe a working electrode with a GOx sensor and a background electrode in which the background electrode has no GOx sensor. The system may then compare the first signal and the second signal to detect ingestion of a medication by the user. The system may generate a sensor glucose value based on the comparison.

Methods, systems, and devices for improved sensors for continuous glucose monitoring

An electrochemical sensor including a working electrode having an arrangement of pillars defining channels between the pillars. The channels increase confinement of a byproduct produced in an electrochemical reaction used during sensing of an analyte, so as to increase interaction of the byproduct with the working electrode. A number of working embodiments of the invention are shown to be useful in amperometric glucose sensors worn by diabetic individuals.

Micro-pillar working electrodes design to reduce backflow of hydrogen peroxide in glucose sensor

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Northridge, CA, United States of America

Xin Heng