Palatin Technologies Incorporated

Xin Chen

Wei Yang

Shubh D Sharma

Yi-Qun Shi

John H Dodd

Melanocortin receptor-specific cyclic peptides of the formula where R, R, R, Rand Rare as defined in the specification, compositions and formulations including the peptides of the foregoing formula, and methods of preventing, ameliorating or treating melanocortin receptor-mediated diseases, indications, conditions and syndromes.

Melanocortin receptor-specific peptides

Lactam-bridged melanocortin receptor-specific cyclic peptides of the formula where R, R, R, R, R, R, R, Rand Rare as defined in the specification, compositions and formulations including the peptides of the foregoing formula, and methods of preventing, ameliorating or treating melanocortin receptor-mediated diseases, indications, conditions and syndromes, including obesity, modulation of feeding behavior, related metabolic syndrome, sexual dysfunction, male erectile dysfunction and female sexual dysfunction.

Lactam-bridged melanocortin receptor-specific peptides

Melanocortin receptor-specific cyclic peptides of the formula where R, R, R, R, R, R, R, R, R, Rand z are as defined in the specification, compositions and formulations including the peptides of the foregoing formula, and methods of preventing, ameliorating or treating melanocortin receptor-mediated diseases, indications, conditions and syndromes.

Methods for use of a melanocortin receptor agonist cyclic peptide of the formula where R, x and y are as defined in the specification, and compositions and formulations including the peptide of the foregoing formula, for preventing, ameliorating or treating female sexual dysfunction.

Melanocortin receptor-specific peptides for treatment of female sexual dysfunction

A melanocortin receptor agonist cyclic peptide of the formula where R, x and y are as defined in the specification, compositions and formulations including the peptide of the foregoing formula, and methods of preventing, ameliorating or treating melanocortin receptor-mediated diseases, indications, conditions and syndromes, including sexual dysfunction such as male erectile dysfunction and female sexual dysfunction.

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Furlong, PA, United States of America

Xin Chen