Shanghai Pharmaceuticals Holding Co., Ltd.

Huazhong University of Science and Technology

China Triumph International Engineering Co., Ltd.

Shanghai Institute of Organic Chemistry, Chinese Acadmeny of Sciences

Xin Cao

Biao Yu

Jing Lu

Yue Ming Zhou

Gang Pei

Shichao Huang

Fuchun Shi

Yuqian An

Ning Wang

Shou Peng

Wei Hong

Junwei Chen

Jiedong Cui

Lifen Shi

Youle Wang

Qiang Gao

The present invention relates to a novel therapeutic drug for a neurodegenerative disease and an application thereof. Provided is a novel compound of formula (I). The compound can effectively facilitate the proliferation of neural stem cells in both in vitro and in vivo experiments and can be used as a treatment approach for facilitating neuroregeneration to fight against cognitive decline associated with aging or a neurodegenerative disease.

Therapeutic drug for neurodegenerative disease and application thereof

The present invention relates to a novel compound for preventing or treating neurodegenerative diseases and use thereof. Provided is a novel compound of Formula (I). The compound can effectively promotes the proliferation of neural progenitor cells in both in vitro and in vivo experiments, and can serves as a treatment approach to promote nerve regeneration to fight against cognition impairment associated with aging and neurodegenerative diseases.

Compound for preventing or treating neurodegenerative disease and application thereof

A pink aluminosilicate glass, comprising: a glass former, a network intermediate oxide, a network modifier oxide, a network former oxide, a network modifier, a colorant and a clarificant, wherein the glass former is SiO, the network modifier oxide is CaO, MgO, KO and NaO, the network former oxide is BO, and the network modifier is ZrOand SrO. This glass is pink in visible light, has a good visual effect, and has a relatively high thermal stability, and can improve the usage safety in harsh working environments.

Pink aluminosilicate glass

Disclosed are a retinoid compound, a preparation method therefor, intermediates thereof and an application thereof. The retinoid compound I of the present invention has a good tumor growth inhibition rate.

Retinoid compound, preparation method therefor, intermediates thereof and application thereof

Growing community of inventors

Shanghai, China

Xin Cao