Medshine Discovery Inc.

Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Jiangsu Aosaikang Pharmaceutical Co., Ltd.

Nanjing Sanhome Pharmaceutical Co., Ltd.

Qilu Pharmaceutical Co., Ltd.

Guangdong Zhongsheng Pharmaceutical Co., Ltd

China Resources Pharmaceutical Holdings Company Limited

Suzhou Genhouse Bio Co., Ltd.

Xile Liu

Shuhui Chen

Charles Z Ding

Lihong Hu

Jian Li

Haiwen Wan

Baoping Zhao

Fei Wang

Lingyun Wu

Chao Ding

Linxia Xiao

Guoping Hu

Lu Zhang

Jun Zhao

Long Zhang

Zhaozhong Ding

Lele Zhao

Wen Jiang

Ning Zhao

Wei Pan

Minghui Zhang

Chuanwen Fan

Yingying Yang

Xiu Jiang

Jinqing Hu

Shansong Zheng

Qingmei Zheng

Yidong Zhu

Disclosed are a pyrimidinyl group-containing tricyclic compound and applications thereof in preparing a cancer-treating medicament. Specifically disclosed are a compound as represented by formula (I), a pharmaceutically acceptable salt of same, or an isomer thereof.

Pyrimidinyl group-containing tricyclic compound serving as c-Met inhibitor

Disclosed is a class of compounds containing arylsultam, and specifically disclosed are a compound represented by formula (II), and a pharmaceutically acceptable salt or an isomer thereof.

Compounds containing benzosultam

Disclosed is a pyrimidine compound acting on an EGFR exon 20 insertion mutation and an ERBB2 exon 20 insertion mutation or a pharmaceutically acceptable salt thereof. 

Pyrimidine compound acting on EGFR and ERBB2

Disclosed is a class of new aryl-phosphorus-oxygen compounds as shown in formula (I) as EGFR kinase inhibitors, and pharmaceutically acceptable salts thereof. 

Aryl-phosphorus-oxygen compound as EGFR kinase inhibitor

Disclosed is a novel quinazoline compound. Specifically, disclosed are a compound represented by the formula (I) and a pharmacologically acceptable salt. 

Quinazoline compound for EGFR inhibition

Disclosed is a fused-ring or tricyclic aryl pyrimidine compound used as a mutation selectivity EGFR inhibitor. Specifically, disclosed is a compound represented by formula (I) and used as an EGFR inhibitor or a pharmaceutically acceptable salt thereof. 

Fused-ring or tricyclic aryl pyrimidine compound used as kinase inhibitor

Disclosed is a spirocyclic aryl phosphorus oxide or sulfide as an ALK inhibitor, particularly, a compound represented by formula (I) as an ALK inhibitor or pharmaceutically acceptable salt thereof. 

Spirocyclic aryl phosphorus oxide and aryl phosphorus sulfide

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Shanghai, China

Xile Liu