Bloodworks

University of Washington

Puget Sound Blood Center

Xiaoyun Fu

Jose Lopez

Junmei Chen

Dominic W Chung

Minhua Ling

Jose Aron Lopez

Barbara A Konkle

Shelby A Cate

Compositions and methods are described for preventing or reducing protein loss due to protein aggregation, denaturation, and absorption to surfaces. Also described are compositions and methods for preventing or reducing the fouling or clogging of medical devices that come into contact with blood, such as catheters. Also described are methods to treat diseases caused by activation of the microvasculature.

Protein stabilizing factors

Compositions and methods for determining the level of thiol and disulfide containing molecules in a sample are provided. The compositions and methods can be used to determine the level of oxidative stress in a subject with or without antioxidant treatment. Also provided are biomarkers of oxidative stress.

Determination of small-molecule thiols and disulfides: protein bound cys and total cysteine as biomarkers of oxidative stress

Compositions and methods are described for preventing or reducing protein loss due to protein aggregation, denaturation, and adsorption to surfaces. Also described are compositions and methods for preventing or reducing the fouling or clogging of medical devices that come into contact with blood, such as catheters. Also described are methods to treat diseases caused by activation of the microvasculature.

Growing community of inventors

Kenmore, WA, United States of America

Xiaoyun Fu