University of Utah Research Foundation

Leland Stanford Junior University

The University of Tennessee Research Foundation

Xiaoyu Xu

Glenn D Prestwich

Thomas P Kennedy

Jianxing Zhang

Narayanam Rao

Jayakumar Rajadas

M Peter Marinkovich

Guanghui Yang

Gabor G Tigyi

Honglu Zhang

Joanna Gajewiak

Jing Gao

Guowei Jiang

Disclosed are methods for the use of a truncated, recombinant laminin-511 for modifying hair growth as well as delivery devices, kits and methods for topically administering truncated, recombinant laminin-511. Furthermore disclosed are delivery devices, kits and methods using modulators of full-length laminin-511 expression or function to decrease hair growth in areas of unwanted hair growth.

Methods for modulating hair growth using truncated laminin-511

Described herein is the synthesis and pharmacology of a series of &#x3b1;-substituted methylene phosphonate analogs, in which the &#x3b1;-CHmoiety is replaced with CHCl or CHBr.

Alpha-chloro and alpha-bromo phosphonate analogs of lysophosphatidic acid and methods of making and using thereof

Described herein is the synthesis of alkylated and semi-synthetic glycosaminoglycosan ethers, referred to herein as 'SAGEs.' The synthesis of sulfated alkylated SAGEs is also described. The compounds described herein are useful in a number of applications including wound healing, drug delivery, and the treatment of a number of inflammatory diseases and skin disorders.

Alkylated semi synthetic glycosaminoglycosan ethers, and methods for making and using thereof

Alkylated semi-synthetic glycosaminoglycosan ethers, and methods of making and using thereof

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Foster City, CA, United States of America

Xiaoyu Xu