Zhejiang Huahai Pharmaceutical Co., Ltd.

Zhejiang Zhuji United Chemicals Co., Ltd.

Advance Will Technology Limited

Xiaoyan Xu

Xiaolin Li

Xiaomei Mu

Jianhua Zhu

Zhensheng Zhong

Bangchi Chen

Qiuju Sheng

Zhiyun Wang

Min Li

Wenquan Zhu

Jinsheng Lin

Baochuan Guan

Dan Li

Tianpei Huang

Libin Hu

Feifei Lan

Xianbo Xu

Hongwei Zhang

Haiping Mu

Zhuoya Zhang

Yonglin Zhang

The application provides a high-purity thermostable crystal form of a substituted 3-isoxazolidinone compound, a preparation method therefor and an application thereof. The High-purity thermostable crystal form is prepared by a particular method of the present technology and is determined by single-crystal X-ray diffraction as an orthorhombic crystal, featuring a space group of P212121 and lattice parameters of a=9.2301(2) Å, b=11.0751(3) Å, c=12.7554(3) A, α=90°, β=90°, and γ=90°. The orthorhombic crystal can be conveniently applied in preparation of agrochemical formulations, such as a suspension concentrate and a water dispersible granule, and the new formulations prepared have a better herbicidal activity and crop safety.

High-purity thermostable crystal form of substituted 3-isoxazolidinone compound, preparation method therefor and application thereof

Disclosed is N-formyl vortioxetine, and also disclosed is a method for preparing the N-formyl vortioxetine and a stable solid preparation of vortioxetine.

N-formyl vortioxetine and preparation method thereof and solid preparation of vortioxetine

Growing community of inventors

Zhejiang, China

Xiaoyan Xu