National Institute for Materials Science

University of Washington

Xiaoyan Liu

Kenji Kitamura

Guozhong Cao

Shunji Takekawa

Kazuya Terabe

Minoru Osada

Takahiro Nagata

Shunichi Hishita

A substrate for surface enhanced Raman spectroscopy analysis (SERS) comprises a ferroelectric single crystal having polarization-inverted patterns of spontaneous polarizations including polarization-inverted portions and non-inverted polarization portions, and metallic dots positioned at only either one polarized surfaces of the polarization-inverted portions and the non-inverted polarization portions. The provided SERS substrate produces a high enhancement effect. A microfluidic device incorporating the SERS substrate is also provided.

Substrate for surface enhanced Raman spectroscopy analysis and manufacturing method of the same, biosensor using the same, and microfluidic device using the same

A method of fixing a polarization-reversed region formed in a ferroelectric single crystal, including preparing a ferroelectric single crystal having a polarization-reversed region; and irradiating an ion beam or a neutral beam on the ferroelectric single crystal. The ferroelectric single crystal is a substantially stoichiometric lithium tantalate single crystal or a substantially stoichiometric lithium niobate single crystal, and the polarization-reversed region is fixed and any back switch and expansion of the polarization-reversed region are suppressed.

Method of fixing polarization-reversed region formed in ferroelectric single crystal

Growing community of inventors

Seattle, WA, United States of America

Xiaoyan Liu