Novartis Ag

Alcon, Inc.

Ciba-geigy Corporation

Alcon Manufacturing, Ltd.

Hoya Corporation

Alcon Research, Ltd.

Xiaoxiao Zhang

Xin Hong

Mutlu Karakelle

Yin Yang

Michael John Simpson

Yan Zhang

Steve VanNoy

Qun Peng

Michael J Simpson

Yueai Liu

Mikhail Boukhny

Yoshitaka Watanabe

Myoung-Taek Choi

Ming Ye

Daniel Robert Carson

Costin Eugene Curatu

James Hoffman

Myoung Choi

Warren E Hill

Blake Harris

Krishnakumar Venkateswaran

Stephen J Vannoy

John Martin Lally

Stephen J Van Noy

Joseph I Weinschenk, Iii

Richard James Mackool

Arthur Bradley

Manfred Hofmann

Son Trung Tran

Son C Tran

Robert D Angelopoulos

Kamal K Das

Juergen Vogt

Michael A Southard

Jihong Xie

Richard Dale Auten

Dan Stanley

K Scott Ellis

Iii Joseph Weinschenk

Michael Simpson

Richard J Mackool

In one aspect, the present invention provides an ophthalmic lens (e.g., an IOL) that includes an optic having an anterior surface and a posterior surface disposed about an optical axis. At least one of the surfaces (e.g., the anterior surface) has a profile characterized by superposition of a base profile and an auxiliary profile. The auxiliary profile can include an inner region, an outer region and a transition region between the inner and the outer regions, where an optical path difference across the transition region (i.e., the optical path difference between the inner and the outer radial boundaries of the transition region) corresponds to a non-integer fraction (e.g., &#xbd;) of a design wavelength (e.g., a wavelength or about 550 nm).

Extended depth of focus (EDOF) lens to increase pseudo-accommodation by utilizing pupil dynamics

An ophthalmic lens includes an optical filter operable to filter out at least visible light having a wavelength less than 450 nm. The lens also includes a first diffractive structure adapted to produce a focus for visible light in a first wavelength range above 550 nm and to reduce longitudinal chromatic aberration to less than one diopter for incoming visible light in the first wavelength range. The lens also includes a second diffractive structure outside the first diffractive structure in a radial direction and adapted to produce a focus for visible light in a second wavelength range between 450 nm and 550 nm. The second diffractive structure is also adapted to reduce longitudinal chromatic aberration for incoming visible light in the second wavelength range to less than one diopter while allowing longitudinal chromatic aberration in the first wavelength range in an amount greater than the first diffractive structure.

IOL with varying correction of chromatic aberration

An accommodating intraocular lens (AIOL) includes an optic adapted to produce a trapezoidal phase shift and a plurality of haptics. Each haptic extends from a haptic-optic junction to at least one transverse arm contacting a capsular bag of the eye, and each haptic has sufficient length and rigidity to stretch a capsular bag of the eye to contact ciliary muscles of the eye. The haptic-optic junctions vault the optic forward relative to the haptics and compression of the haptics by the ciliary muscles moves the anterior optic forward. A combined accommodative power produced by the motion of the anterior optic and the trapezoidal phase shift is at least 0.5 Diopters.

Accommodating intraocular lens using trapezoidal phase shift

In one aspect, the present invention provides a method of designing an intraocular lens (IOL) to address variations of at least one ocular parameter in a population of patient eyes. The method can include establishing at least one eye model in which the ocular parameter can be varied over a range exhibited by the population. The eye model can be employed to evaluate a plurality of IOL designs in correcting visual acuity for eyes in the patient population. An IOL design that provides a best fit for visual performance over at least a portion of the parameter range can then be selected.

Correction of higher order aberrations in intraocular lenses

A method for calculating the required power of a toric implant by using both the measured pre-operative corneal astigmatism and the predicted surgically-induced post-operative astigmatism. The surgically-induced post-operative astigmatism is predicted using power vector analysis of the surgical technique employed by the surgeon. Such a method provides a more accurate method of calculating the required post-operative refractive power of the implant. The method can be implemented manually, but preferably is automated by implementation on a computer through appropriate software.

Method of calculating the required power of a toric implant

In one aspect, the present invention provides an ophthalmic lens (e.g., an IOL) that includes an optic having an anterior surface and a posterior surface disposed about an optical axis. At least one of the surfaces (e.g., the anterior surface) has a profile characterized by superposition of a base profile and an auxiliary profile. The auxiliary profile can include an inner region, an outer region and a transition region between the inner and the outer regions, where an optical path difference across the transition region (i.e., the optical path difference between the inner and the outer radial boundaries of the transition region) corresponds to a non-integer fraction (e.g., &#xbd;) of a design wavelength (e.g., a wavelength of about 550 nm).

In one aspect, the present invention provides a method for correcting vision that employs two lenses, at least one of which is a multifocal lens, with different focusing characteristics for use in the two eyes of the patient. The visual performance of each lens (e.g., visual contrast or acuity) is selected in accordance with a predefined relation so as to optimize the binocular visual performance provided by the combination of the lenses.

Alternating optical system: mixing and matching optics to maximize binocular visual benefits

In one aspect, the present invention provides a two-element ophthalmic lens in which a lateral shift of the elements relative to one another can cause a variation not only in a spherical power provided by the lens but also in spherical aberration exhibited by that lens. In some implementations, the thickness profiles of the two elements are designed such that the variation in spherical aberration is positively correlated with that of the spherical power of the lens.

Two-element system to provide an ease of accommodation with variable-spherical aberration control

An intraocular lens device that includes an intraocular lens optics that provides at least two powers of magnification one being near vision power and the other being distance vision power. The lens optics has surface modulations that are responsible for providing the near vision power. The zone structure provides an add power of over 6 diopters. The add power indicative of an extent that the near vision focusing power is greater than the distance vision focusing power.

Intra-ocular device with multiple focusing powers/optics

In one aspect, the present invention provides a method of correcting vision, which comprises determining a residual accommodation exhibited by a natural, crystalline lens of an eye, and selecting a multifocal intraocular lens (IOL), which exhibits a far-focus optical power (e.g., in a range of about &#x2212;15 to about +50 Diopters (D)) and an add power (e.g., in a range of about 1 D to about 4 D), for implantation in the eye while retaining the natural lens. The add power of the IOL is selected as a function of the residual accommodation such that a combination of the IOL and the natural lens provides a visual contrast greater than about 10% at a spatial frequency of about 20 cycles/degree for viewing objects at a distance greater than about 30 cm from the eye.

Intermediate vision with phakic multifocal optics utilizing residual accommodations

A two optic accommodative lens system wherein at least one of the optics is deformable. When compressed by the capsular bag, the two optics press against each other, deforming at least one of the optics. As a result, the interface where the two optics meet changes shape, thereby altering the refractive power of the lens system.

Accommodative intraocular lens system

The present invention is generally directed to accommodative intraocular lenses (IOLs) that exhibit a dynamic spherical aberration as a function of accommodative power. By way of example, in one aspect, the present invention provides an intraocular lens (IOL) having an anterior optical element, a posterior optical element, and a mechanism for coupling the anterior and posterior elements so as to allow axial movement of those elements relative to one another for providing accommodation when the lens is implanted in a patient's eye. Each of the anterior and the posterior elements includes at least one aspherical surface, where the asphericities of the surfaces are adapted to provide a combined spherical aberration that varies with accommodation.

Accommodative IOL with dynamic spherical aberration

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Fort Worth, TX, United States of America

Xiaoxiao Zhang