Arizona State University

Xiaowei Liu

Yung Chang

Sidney M Hecht

Joseph Leal

Sriram Sokalingam

Viswanath Arutla

Hao Yan

Fei Zhang

Xiaodong Qi

Provided herein are methods for rational design of nicotine haptens. More particularly, provided herein are methods for designing, selecting, and synthesizing nicotine haptens and nicotine hapten conjugates. Also provided herein are novel nicotine haptens and methods for using nicotine haptens to treat nicotine addiction.

Methods of rational nicotine hapten design and uses thereof

Certain embodiments provide RNA nanostructure (e.g., comprising one single-stranded RNA (ssRNA) molecule, wherein the RNA nanostructure comprises at least one paranemic cohesion crossover), as well as compositions and methods of use thereof. In certain embodiments, such RNA nanostructures are immuno-modulatory (e.g., immuno-stimulatory).

RNA nanostructures and methods of making and using RNA nanostructures

Growing community of inventors

Tempe, AZ, United States of America

Xiaowei Liu