H. Lee Moffitt Cancer Center and Research Institute, Inc.

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Domenico Coppola

Biomarkers, methods, assays, and kits are provided for predicting the progression of Barrett esophagus in a subject to esophageal cancer. The method can therefore also be used to select the appropriate treatment for a subject diagnosed with Barrett esophagus. Disclosed are methods for predicting the progression of Barrett esophagus in a subject to esophageal cancer. The method can therefore also be used to select the appropriate treatment for a subject diagnosed with Barrett esophagus. For example, the disclosed biomarkers, methods, assays, and kits can be used to predict the benefit of surgery, laser treatment, radiofrequency ablation, radiation therapy, chemotherapy, or any combination thereof for a subject diagnosed with Barrett esophagus based on whether they are predicted to progress to esophageal cancer.

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Yardley, PA, United States of America

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