Risen (suzhou) Pharma Tech Co., Ltd.

Shanghai Junshi Biosciences Co., Ltd.

Shanghai Junshl Biosciences Co., Ltd.

Xiaolin Zhang

Xianqi Kong

Jiasheng Lu

Jiamin Gu

Gang Chen

Feng Zhou

There are provided compounds of Formula I, and pharmaceutically acceptable salts and esters thereof, and pharmaceutical compositions thereof, used for inhibition or modulation of the activity of cyclin dependent kinases (CDK) and/or glycogen synthase kinase-3 (GSK-3), for the treatment of disease states or conditions mediated by cyclin dependent kinases and/or glycogen synthase kinase-3, including cancers.

Prodrugs of a CDK inhibitor for treating cancers

There are provided compounds of Formula I, and pharmaceutically acceptable salts and esters thereof, and pharmaceutical compositions thereof, used for inhibition or modulation of the activity of cyclin dependent kinases (CDK) and/or glycogen synthase kinase-3 (GSK-3), for the treatment of disease states or conditions mediated by cyclin dependent kinases and/or glycogen synthase kinase-3, including cancers. 

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Suzhou, China

Xiaolin Zhang