Risen (suzhou) Pharma Tech Co., Ltd.

Shanghai Junshi Biosciences Co., Ltd.

Xiaolin He

Xianqi Kong

Jiamin Gu

Jiasheng Lu

Xiang Ji

Dongqing Zhu

Lin Wang

Dongdong Wu

Daiqiang Hu

Xiuchun Zhang

Xinyong Lv

Jinchao Ai

Jinchao Al

There are provided isotope-enriched compounds containing stable heavy isotope-enriched amide functional groups for modulating the pharmacokinetic profile, metabolic profile, and/or delivery efficiency of a drug or prodrug, as well as its therapeutic or prophylactic efficacy and/or adverse effects. Use of the isotope-enriched amide-containing drugs and prodrugs for the treatment or prevention of disease states and conditions is also provided.

Stable heavy isotopes in amide functional groups and uses thereof

There are provided compounds of Formula (A) and pharmaceutically acceptable salts and esters thereof, and pharmaceutical compositions thereof, used for the prevention or treatment in a manual of joint and bone disorders such as arthritis and osteoporosis.

Glucosamine derivatives for the prevention or treatment of joint disorders

There are provided compounds of Formula (A) and pharmaceutically acceptable salts and esters thereof, and pharmaceutical compositions thereof, used for the prevention or treatment in a mammal of joint and bone disorders such as arthritis and osteoporosis.

Glucosamine derivatives and pharmaceutical uses thereof

Growing community of inventors

Jiangsu, China

Xiaolin He