Merck Sharp + Dohme Corp.

Other

Petrochina Company Limited

Chinese Research Academy of Environmental Sciences

Xiaoli Zhao

Hua Zhou

Neville J Anthony

Jason David Katz

Feng Shi

Meredeth Ann McGowan

Kin Chiu Fong

Changwei Mu

Fengchang Wu

Baijun Ye

Bin Wang

Ying Wang

Lihu Yang

Qiang Fu

Tao Yang

Yong Wu

Qiang Li

Michael D Altman

Joey Lee Methot

Solomon D Kattar

Rong Zhang

Jianmin Fu

Abdelghani Achab

Yongqi Deng

Matthew Christopher

Francesc Xavier Fradera Llinas

Yuan Tian

Liping Yang

Chaomin Li

Jiang Yu

Youzhi Zheng

Huiyun Ma

Ji Chen

Yudith Garcia

Haiqing Liao

Bo Kong

Yabin Li

Xiansheng Leng

Xiaona Wang

Sixing Zhang

Yingchen Bai

Qiyan Tan

Fuyun Wang

Libin Jiao

Meredeth A Mcgowan

Hongwei Xia

Yunsong Mu

Xiaojiao Wang

Yiguo He

Fenglin Guo

Congjing Liu

Minghua Xie

Yu Sang

Yixin Tan

Abdelghani Abe Achab

Matthew P Christopher

Neville John Anthony

A Cu catalyst based on a metal organic framework as well as a preparation method and a use thereof is provided. The Cu catalyst based on a metal organic framework comprises composite particles with catalytic activity sites composed of copper in different oxidization states and a porous carbonized layer with a supporting effect. The method for preparing the catalyst includes the following steps: 1) preparing a metal organic framework Cu-MOF; and 2) carbonizing the metal organic framework Cu-MOF. The Cu catalyst can be used in aqueous phase catalysis to catalytically decompose organic pollutants in water.

Cu catalyst based on metal organic framework, preparation method and use thereof

The invention provides a method and device for measuring the elasticity of hardened cement for cementing of oil-gas wells. The measurement method comprises: determining the loading and unloading rates of the hardened cement; determining the maximum loading on the hardened cement; determining the experimental temperature and the experimental pressure of the hardened cement; establishing a stress-strain curve for the hardened cement; and describing the elasticity of the hardened cement with the degree of strain recovery of the hardened cement in different cycles, and describing the mechanic integrity of the hardened cement with the degree of damage to the hardened cement in different cycles. The invention further provides a device for measuring the elasticity of hardened cement for cementing of oil-gas wells. The measurement method and device of the present invention provide a universal comparing platform for research on hardened cement modification as well as examination of domestic and foreign special cement slurry systems, which is of great significance in evaluation of well hole integrity and well life.

Method and device for determining elasticity of cement stone utilized in well cementing of oil-gas well

The present invention relates to a fresh water acute criteria prediction method based on a quantitative structure-activity relationship for metals. An unknown toxic endpoint of a metal is predicted according to a quantitative relationship between structural characteristics of heavy metal ions and acute toxicity effects of aquatic organisms, and hazard concentrations for protecting the aquatic organisms of different proportions are derived from sensitivity distribution analysis on different species. The fresh water acute criteria prediction method is a method for establishing a metal toxicity predictive model by integrating physicochemical structural parameters of heavy metals and toxic mechanisms of different aquatic organisms and applying the metal toxicity predictive model to prediction of an unknown criteria reference value.

Fresh water acute criteria prediction method based on quantitative structure-activity relationship for metals

The instant invention provides compounds of formula (I) which are PI3K-delta inhibitors, and as such are useful for the treatment of PI3K-delta-mediated diseases such as inflammation, asthma, COPD and cancer. 

Purine inhibitors of human phosphatidylinositol 3-kinase delta

The instant invention provides compounds of formula I which are PI3K-delta inhibitors, and as such are useful for the treatment of PI3K-delta-mediated diseases such as inflammation, asthma, COPD and cancer. 

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Beijing, China

Xiaoli Zhao