Adagene Inc.

Xiaohong She

Fangyong Du

Jun Chen

Guizhong Liu

Peter Cheung

Yan Li

Peter Peizhi Luo

The present disclosure provides antibodies that bind to human CD137 or antigen binding fragments thereof, nucleic acid encoding the same, therapeutic compositions thereof, and their use to enhance T-cell function to upregulate cell-mediated immune responses and for the treatment of T cell dysfunctional disorders, such as tumor immunity, and for the treatment of cancer.

Anti-CD137 molecules and use thereof

Provided are antibodies that bind to human CD137 or antigen binding fragments thereof, nucleic acid encoding the same, therapeutic compositions thereof, and their use to enhance T-cell function to upregulate cell-mediated immune responses and for the treatment of T cell dysfunctional disorders, such as tumor immunity, and for the treatment of cancer.

Method for treating cancer using anti-CD137 antibody

Growing community of inventors

Suzhou, China

Xiaohong She