Sichuan Yingrui Pharmaceutical Technology Company

Chongqing Lummy Pharmaceutical Co., Ltd.

Xiaohai Tang

Yuanfang Huang

Cheng Zeng

Yu Qiu

Pingfang Xia

Xin Song

Lilin Peng

The disclosure relates to a pectin-adriamycin conjugate, and discloses a preparation method and use of the conjugate above. The pectin-adriamycin conjugate of the disclosure has a completely new chemical structure and can be accumulated in a malignant tumor tissue for a long time with a high concentration in a targeting manner so as to achieve the purposes of enhancing effects and reducing toxicity, and the indications are chemotherapies of various solid malignant tumors.

Pectin-adriamycin conjugate as well as preparation method and use thereof

The present invention provides a nanocarbon-iron composite system which is a composite structure formed by interaction of acid-treated nanocarbon serving as a carrier, with and ferrous ions and/or ferric ions in an iron salt. In an in-vitro experiment and an animal experiment, the nanocarbon-iron composite system of the present invention shows a very efficient inhibition effect on solid tumors containing liver cancer, breast cancer and cervical cancer and has an excellent targeting property. Accordingly, the present invention further provides a preparation method of the nanocarbon-iron composite system, use of the nanocarbon-iron composite system in preparation of a drug for treating solid tumors, and a suspension for injection based on the nanocarbon-iron composite system.

Nanocarbon-iron composite system as well as composition, preparation method and use thereof

Growing community of inventors

Chongqing, China

Xiaohai Tang