Wisconsin Alumni Research Foundation

Xiaoguang Wang

Nicholas Lawrence Abbott

Marco Antonio Bedolla Pantoja

Emre Bukusoglu

Youngki Kim

Systems and methods for the controlled release of a guest composition that is sequestered within a host composition made up of an anisotropic fluid are disclosed. The guest composition is immiscible in the host composition, thus forming an interface between the compositions upon which elastic repulsion forces act to prevent the release of the guest composition from the host composition. The disclosed systems and methods work by changing the elastic repulsion forces and/or introducing one or more counter forces such that the elastic repulsion forces are no longer sufficient to prevent release of the guest composition. Exemplary methods include mechanically changing the host material (e.g., changing its temperature) or inducing a chemical (e.g., electrostatic) attraction sufficient to overcome the elastic repulsion forces. The disclosed systems and methods can be used for a variety of applications requiring 'on-demand' delivery of a chemical composition.

Activated release of target material trapped in anisotropic fluids

Methods and compositions for detecting a targeted analyte, such as volatile organic compound (VOCs), are disclosed. Specifically, a cholesteric liquid crystal composition comprising a nematic liquid crystal and a chiral dopant transitions to a liquid crystal blue phase or undergoes other optical changes when in contact with a sample containing the analyte. The phase transition can be readily detected with the naked eye. The disclosed methods and compositions may be used in, for example, dosimeters for detecting analyte (e.g., VOC) exposure. Methods and compositions for producing arrays of liquid crystal thin films are also disclosed. The surface between the microwells in a microwell array is coated with a liquid-crystal-phobic material, such as a fluorinated polymer or a fluorinated silane, creating isolated microwell domains that are preferentially wetted by liquid crystal. Liquid crystal can be added to the microwell domains by simple techniques such as spin coating.

Method of detection of volatile organic compounds using liquid crystals that form a blue phase; and device for stabilization and thickness control of liquid crystal films

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Madison, WI, United States of America

Xiaoguang Wang