Brigham Young University

Xiaofeng Xie

Milton L Lee

H Dennis Tolley

Paul B Farnsworth

Jesse A Contreras

Luke T Tolley

Jacolin A Murray

Tai Van Truong

Dennis H Tolley

A system and method for separating the functions of a liquid chromatography (LC) system into physically separate systems that allow for a more versatile LC system, wherein an LC device provides columna liquid solvent, a sample, and a pump and injector that pushes the sample in the solvent to an output port, and providing an attachable module containing a module input port, a column, a heater for the column, and at least one detector for on-column detection, then attaching the module to the LC device using a press-fit connection that enables the sample in the solvent to be pumped through the column to the at least one detector in order to separate, identify and quantify substances in the sample and transmit results from the at least one detector to the LC system for collection and analysis.

Integrated column and detector in a module for liquid chromatography

A system for providing standard mixtures of volatile and semi-volatile organic compounds for simultaneous GC and MS calibration in a calibration vial, wherein calibration mixtures are prepared by diluting calibration analytes in granular PDMS such that most of the analytes are in the PDMS phase and the sample can then be taken from the analytes in the headspace vapor in the calibration vial, wherein a reliable calibration sample can be taken from the calibration vial because the analytes in the PDMS phase and the headspace vapor are in thermodynamic equilibrium, and wherein the method provides solvent-less sampling, long-time stability, ease of use, is quantifiable, and related to temperature.

Simple equilibrium distribution sampling device for GC-MS calibration

Growing community of inventors

Provo, UT, United States of America

Xiaofeng Xie