Becton Dickinson and Company Limited

Xiaofei Chang

Michael A Brasch

Mei Yang-Woytowitz

Timothy M Wiles

Brent Ronald Pohl

Charles C Yu

Patrick Shawn Beaty

Ming-hsiung Yeh

Liping Feng

Ben Turng

Gary F Hershner

Patrick R Murray

Eric Ursprung

Dwight Livingston

Ammon David Lentz

Song Shi

Kevin Bailey

James Y Zhou

Gerard Lotz

Ming-Hsiung Yeh

A container for culturing a blood sample. The container has a reservoir that is no larger than about 40 ml in volume with culture media therein varying in amount by volume 0.5 ml to about 20 ml. The container is adapted to receive a blood sample drawn from a patient, wherein the blood volume is about 1 ml to about 20 ml. In some embodiments the ratio of blood volume to culture media volume is about 2:1 to about 1:2 and the volume of blood does not exceed about 10 ml. In some embodiments, the media is lytic media. A method for using the container to culture a blood sample is also contemplated. In such method, the container is inoculated with the blood sample. In certain embodiments, the volume of the blood sample does not exceed 10 mls.

Blood culture system with low media volume

An apparatus and associated methods of use for a controlled combination of reagents is disclosed. The apparatus includes a vessel, a vessel insert, and a cap element. The vesselhas a body portionfor receiving a biological sample. The vessel insertreceives at least one reagent therein. Preferably, the vessel insertis received in a portionof the vessel. The cap elementis attached to the vesselto secure the vessel insertin the vessel. During use, the vessel insertis adapted to release its contents when the biological sample is introduced into the body portionof the vesselupon application of an intermixing force to the vessel insert. A variety of intermixing forces may be applied, depending upon the embodiment of the present invention and its associated methods of use.

Blood culture bottles with mechanisms for controlled release of substances into culture media

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Timonium, MD, United States of America

Xiaofei Chang