Tianjin University

Tianjin Polytechnic University

Tianjin Toptech Bio-Science & Technology Co., Ltd.

Xiaodong Zhang

Changfa Xiao

Fengzhou Fang

Zhongjun Qiu

Lihong Ye

Xiaotang Hu

Zongwei Xu

Tengfei Dai

Weiwei Yin

Nana Li

Dan Guo

Yunhui Chen

Disclosed is a polyvinylidene fluoride/ultra-high molecular weight polyethylene blend microporous membrane and preparation method thereof, which belongs to the field of microporous membrane. The blend microporous membrane has good hydrophobicity, mechanical properties and permeability. The preparation method includes: preparing a suspension by polyvinylidene fluoride, ultra-high molecular weight polyethylene, antioxidant and diluent; then feeding the obtained suspension into a twin-screw extruder, and the cast membrane gel extruded from the outlet is directly injected into a metal mold for injection molding; the mold temperature and the outlet temperature of the extruder are the same, and the cavity surface of the mold has micro-prism array structure; then cooling the mold in aqueous medium to obtain a nascent gel membrane; drying the obtained nascent gel membrane in a freeze dryer after removal of the diluents by extraction. The prepared membrane can be used in the membrane separation technology such as membrane distillation.

Polyvinylidene fluoride/ultra-high molecular weight polyethylene blend microporous membrane and preparation method thereof

The present invention relates to the field of polypeptide medicine, and relates to polypeptides against hepatitis B virus X Protein and uses thereof. Specifically, the present invention relates to polypeptides comprising D-amino acids, which have a function of inhibiting hepatitis B virus X protein, and inhibit HBx activities, inhibit replication of hepatitis B virus DNA and expression of related antigens (e.g., HBeAg) at molecular level, cellular level and animal level, and further inhibit hepatitis and hepatic cirrhosis caused by hepatitis B virus infection and liver cancer that occurs on the basis of hepatic cirrhosis. The polypeptides can be widely used in the prevention and treatment of liver diseases after hepatitis B infection, including hepatitis, hepatic cirrhosis, and liver cancer.

Anti-hepatitis B virus X protein polypeptide pharmaceutical

The invention relates to a new technology which uses a surface modification method for ultra-precision machining, and in particular relates to a particle beam-assisted ultraprecision machining method for single-crystal brittle materials. The invention, the particle beam-assisted ultra-precision machining method for single-crystal brittle materials, can significantly improve machining accuracy, reduce surface finish and greatly reduce tool wear during ultra-precision machining of brittle materials. The method adopts the technical proposal that the method comprises of the following steps: a) utilizing simulation software to simulate modification parameters according to cutting depth, surface roughness and other machining requirements; b) using particle beams to bombard or irradiate the surface of a single-crystal brittle material to be machined, according to the energy and fluence obtained from the simulation results; c) utilizing ultra-precision cutting (or grinding) technology to perform ultra precise cutting on the single-crystal material which is bombarded or irradiated by the particle beams; and d) measuring and characterizing the surface quality of the machined material and comparing the improvement of the machined surface quality with that of the unmodified machined surface. The method is mainly used for machining the single-crystal brittle materials.

Particle beam-assisted ultra-precision machining method for single-crystal brittle materials

Growing community of inventors

Tianjin, China

Xiaodong Zhang